Evidence map›Paper›PMID 34178454›Full record

ArticlePeerJ2021

Maximization of information transmission influences selection of native phosphorelay architectures.

Rui Alves, Baldiri Salvadó, Ron Milo, Ester Vilaprinyo, Albert Sorribas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rui Alves *Ciències Mèdiques Bàsiques, Universitat de Lleida, Lleida, Spain.
Baldiri Salvadó *Ciències Mèdiques Bàsiques, Universitat de Lleida, Lleida, Spain.
Ron MiloPlant and Environmental Science, Weizmann Institute of Science, Rehovot, Israel.
Ester VilaprinyoCiències Mèdiques Bàsiques, Universitat de Lleida, Lleida, Spain.
Albert SorribasCiències Mèdiques Bàsiques, Universitat de Lleida, Lleida, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorelays are signal transduction circuits that sense environmental changes and adjust cellular metabolism. Five different circuit architectures account for 99% of all phosphorelay operons annotated in over 9,000 fully sequenced genomes. Here we asked what biological design principles, if any, could explain selection among those architectures in nature. We began by studying kinetically well characterized phosphorelays (Spo0 of

Indexed as

Bacterial signal transductionBiological design principlesBiological information transmissionMathematical modellingSelection

Identifiers

PMID34178454
PMCPMC8199921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.