Evidence map›Paper›PMID 34178319›Full record

ArticleAnnals of medicine and surgery (2012)2021

Impact of Thyroid Autoimmunity in euthyroid women on the outcomes of In Vitro Fertilization.

Ahed Hamad, Nawras Alhalabi, Nazht Nmr, Fatima Abbas, Hisham Al-Hammami, Nazir Ibrahim, Marwan Alhalabi

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ahed HamadFaculty of Medicine, Damascus University, Damascus, Syria.
Nawras AlhalabiFaculty of Medicine, Damascus University, Damascus, Syria.
Nazht NmrFaculty of Medicine, Damascus University, Damascus, Syria.
Fatima AbbasFaculty of Medicine, Damascus University, Damascus, Syria.
Hisham Al-HammamiDepartment of Obstetrics and Gynecology, Faculty of Medicine, Syrian Private University, Damascus, Syria.
Nazir IbrahimDepartment of Internal Medicine, Faculty of Medicine, Syrian Private University, Damascus, Syria.
Marwan AlhalabiDivision of Reproductive Medicine, Embryology and Genetics, Faculty of Medicine, Damascus University, Damascus, Syria.
Damascus University · SYSyrian Private University · SYDamascus Hospital · SY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInfertility is inadequately acknowledged as a problem in developing countries. Thyroid Autoimmunity (TAI) has been neatly investigated for its association with unfavorable pregnancy and reproductive consequences. We aim to evaluate Clinical Pregnancy Rate (CPR) as a primary outcome following In Vitro Fertilization/Intra Cytoplasmic Sperm Injection (IVF/ICSI) in women with Thyroid Autoimmunity (TAI).

methodsA Retrospective cohort study included 584 women who underwent IVF/ICSI treatment between November 2012 and April 2017 in Orient Hospital, Damascus, Syria. Patients were tested for TAI before IVF/ICSI procedure.

resultsCPR did not significantly differ between TAI positive and TAI negative groups (p > 0.05). Subgroup analysis for only primary infertility patients showed a statistically significant difference in CPR between TAI positive and TAI negative groups.

conclusionAlthough several arguments were in favor of the relation between IVF/ICSI outcomes and Thyroid autoimmune disease, the presence of TAI positivity did not adversely affect the clinical pregnancy rate.

Indexed as

Clinical pregnancy rate (CPR)Intra cytoplasmic sperm injection (ICSI)In vitro fertilization (IVF)SyriaThyroid autoimmunity (TAI)

Identifiers

PMID34178319
PMCPMC8214029
OpenAlexW3169308073

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.