Evidence map›Paper›PMID 34178195›Full record

ArticleRadiology case reports2021

Disseminated histoplasmosis leading to end stage liver failure in immunocompetent patient: case report and review of literature.

Darshan Gandhi, Tanmay Gandhi, Adam Wolfe, Asim Kichloo, Jagmeet Singh, Kenneth P Batts, Love Patel

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Darshan GandhiDepartment of Diagnostic Radiology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N St. Clair St, Suite 800, Chicago, IL 60611, USA.
Tanmay GandhiMaulana Azad Medical College, 2, Bahadur Shah Zafar Marg, New Delhi, Delhi 110002, India.
Adam WolfeInternal Medicine Resident Physician, Graduate Medical Education, Abbott Northwestern Hospital, Minneapolis, MN 55407, USA.
Asim KichlooCentral Michigan University School of Medicine, 1280 East Campus Dr, Mt Pleasant, MI 48858, USA.
Jagmeet SinghGeisinger Commonwealth School of Medicine, 525 Pine St, Scranton, PA 18510, USA.
Kenneth P BattsDepartment of Pathology, Abbott Northwestern Hospital, Allina Health, 800 E 28th Street, Minneapolis, MN 55407, USA.
Love PatelDepartment of Internal Medicine, Abbott Northwestern Hospital, Allina Health, 800 E 28th Street, Minneapolis, MN 55407, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histoplasmosis is the fungal infection caused by Histoplasma capsulatum fungus. It is commonly found in a few endemic areas in the United States, where there is a large number of birds or bats and can spread through their droppings. Disseminated histoplasmosis is a severe manifestation of the fungal infection which is commonly seen in individuals with underlying immunosuppression. Our case is an unusual case of disseminated histoplasmosis in a 60-year-old, immunocompetent male patient with a history of significant alcohol abuse, which led to end stage liver failure. While the patient showed some signs of improvement initially upon beginning the treatment, he ultimately continued to deteriorate despite treatment due to an overwhelming histoplasmosis infection. This case demonstrates the importance of keeping a high index of suspicion even amongst immunocompetent patients with no obvious exposure to risk factors. It also shows that timely diagnosis with a high index of suspicion is required with an integrated treatment approach.

Indexed as

CT scanDisseminated histoplasmosisFungalHistoplasmosisInfectionUSG

Identifiers

PMID34178195
PMCPMC8213978

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.