Evidence map›Paper›PMID 34178127›Full record

ArticleExperimental and therapeutic medicine2021

Clinical-dermoscopic similarities between atypical nevi and early stage melanoma.

Cristina-Raluca Jitian Mihulecea, Simona Frățilă, Maria Rotaru

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Dermoscopy and the Early Melanoma Concept.International journal of dermatology · 2026
    Review
  2. Article
  3. FluorescenceExperimental and therapeutic medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review: The Key Factors to Melanomagenesis.Life (Basel, Switzerland) · 2023
    Review
  8. [Deep learning-based fully automated intelligent and precise diagnosis for melanocytic lesions].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022
    Article
  9. Clinical EvaluationIn vivo (Athens, Greece)
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cristina-Raluca Jitian MihuleceaDermatology Clinic, Emergency Clinical County Hospital of Sibiu, 550245 Sibiu, Romania.
Simona FrățilăFaculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Maria RotaruDermatology Clinic, Emergency Clinical County Hospital of Sibiu, 550245 Sibiu, Romania.
University of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical (Clark) nevi are benign tumors that may be considered precursors of melanoma. Many studies acknowledge a linear progression from typical to atypical nevi that eventually transform into melanoma. It is often challenging to differentiate a Clark nevus from melanoma, especially in its early stages, due to their clinical, dermoscopic, and histological resemblance. Dermoscopy is a powerful tool in early melanoma diagnosis, but it is a subjective method of examination. Therefore, the use of dermoscopic algorithms and checklists can overcome this issue. In the case of a difficult diagnosis, since both dermoscopy and histopathological exam are subjective methods of examination, modern molecular biology techniques can be used to distinguish between benign and malignant tumors. This study aimed to test the accuracy of specific clinical and dermoscopic criteria in order to distinguish between benign and malignant tumors, with a secondary objective to provide an overview of the clinical and dermoscopic features of atypical nevi and melanoma. In the present study, dermoscopic algorithms did not necessarily help distinguish benign and malignant tumors but demonstrated that nevi and melanoma have similar characteristics.

Indexed as

atypical nevidermoscopyearly diagnosishistologymelanoma

Identifiers

PMID34178127
PMCPMC8220634
OpenAlexW3170774105

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.