Evidence map›Paper›PMID 34177999›Full record

ArticleFrontiers in plant science2021

Engineering Betalain Biosynthesis in Tomato for High Level Betanin Production in Fruits.

Ramona Grützner, Ramona Schubert, Claudia Horn, Changqing Yang, Thomas Vogt, Sylvestre Marillonnet

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Plants (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Evolution of aromatic amino acid metabolism in plants: a key driving force behind plant chemical diversity in aromatic natural products.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Engineering a complex, multiple enzyme-mediated synthesis of natural plant pigments in the silkworm,Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ramona GrütznerDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany.
Ramona SchubertDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany.
Claudia HornDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany.
Changqing YangDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany.
Thomas VogtDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany.
Sylvestre MarillonnetDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany.
Leibniz Institute of Plant Biochemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Betalains are pigments found in plants of the Caryophyllales order, and include the red-purple betacyanins and the yellow-orange betaxanthins. The red pigment from red beets, betanin, is made from tyrosine by a biosynthetic pathway that consists of a cytochrome P450, a L-DOPA dioxygenase, and a glucosyltransferase. The entire pathway was recently reconstituted in plants that do not make betalains naturally including potato and tomato plants. The amount of betanin produced in these plants was however not as high as in red beets. It was recently shown that a plastidic arogenate dehydrogenase gene involved in biosynthesis of tyrosine in plants is duplicated in

Indexed as

betalainsbetanincyclo-DOPAfood colorantheterologous hostmetabolic pathway engineeringplant secondary metabolites

Identifiers

PMID34177999
PMCPMC8220147
OpenAlexW3166569096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.