Evidence map›Paper›PMID 34177864›Full record

ArticleFrontiers in microbiology2021

Characterization of Non-selected Intermolecular Gene Conversion in the Polyploid Haloarchaeon

Daniel Wasser, Andreas Borst, Mathias Hammelmann, Katharina Ludt, Jörg Soppa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel WasserInstitute for Molecular Biosciences, Biocentre, Goethe-University, Frankfurt, Germany.
Andreas BorstInstitute for Molecular Biosciences, Biocentre, Goethe-University, Frankfurt, Germany.
Mathias HammelmannInstitute for Molecular Biosciences, Biocentre, Goethe-University, Frankfurt, Germany.
Katharina LudtInstitute for Molecular Biosciences, Biocentre, Goethe-University, Frankfurt, Germany.
Jörg SoppaInstitute for Molecular Biosciences, Biocentre, Goethe-University, Frankfurt, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene conversion is defined as the non-reciprocal transfer of genetic information from one site to a homologous, but not identical site of the genome. In prokaryotes, gene conversion can increase the variance of sequences, like in antigenic variation, but can also lead to a homogenization of sequences, like in the concerted evolution of multigene families. In contrast to these intramolecular mechanisms, the intermolecular gene conversion in polyploid prokaryotes, which leads to the equalization of the multiple genome copies, has hardly been studied. We have previously shown the intermolecular gene conversion in halophilic and methanogenic archaea is so efficient that it can be studied without selecting for conversion events. Here, we have established an approach to characterize unselected intermolecular gene conversion in

Indexed as

archaeagene conversionHaloferax volcaniiheterozygous cellspolyploidyprotoplast fusionunselected segregation

Identifiers

PMID34177864
PMCPMC8223754
OpenAlexW3167510547

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.