SynthesisFrontiers in psychiatry2021
International Expert Opinions and Recommendations on the Use of Melatonin in the Treatment of Insomnia and Circadian Sleep Disturbances in Adult Neuropsychiatric Disorders.
Abstract readSystematic Review
In one paragraph
Synthesis in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy and Acceptability of Licensed and Off-Label Pharmacological Interventions for Insomnia in Patients With Severe Mental Illness: A Systematic Review and Meta-Analysis of Randomised Trials.Acta psychiatrica Scandinavica · 2025Pooled it
- Treatment of Early-Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children.Acta psychiatrica Scandinavica · 2025Pooled it
- Melatonin Treatment for Sleep Disorders in Parkinson's Disease: A Meta-Analysis and Systematic Review.Frontiers in aging neuroscience · 2022Pooled it
- Melatonin and Its Analogs for Prevention of Post-cardiac Surgery Delirium: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Efficacy of clonidine and melatonin for treating insomnia in anxious children: a randomized comparison.BMC pediatrics · 2026Trial
- Bioavailability of Melatonin after Administration of an Oral Prolonged-Release Tablet and an Immediate-Release Sublingual Spray in Healthy Male Volunteers.Drugs in R&D · 2023Trial
- Melatonin in Clinical Practice: Grey Zones Between Chronobiology, Insomnia and Consumer Supplementation.Clocks & sleep · 2026Article
- Suicidal Ideation Following a Single Dose of Melatonin in a Patient With Major Depressive Disorder: A Case Report.Clinical case reports · 2026Article
- Melatonin: Some Aspects of Biochemistry, Physiology, and Pharmacology.Advances and technical standards in neurosurgery · 2026Review
- Detailed Review of Melatonin and its Role in Managing the Symptoms of Depression.Current molecular medicine · 2026Review
- Article
- Therapeutic Potential of Melatonin in Functional Dyspepsia.The Korean journal of helicobacter and upper gastrointestinal research · 2025Article
- Article
- Managing comorbid sleep issues in patients with attention-deficit/hyperactivity disorder.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Article
- The optimal system of care for the management of delayed sleep onset in adult ADHD in the UK: a modified Delphi consensus.Frontiers in psychiatry · 2025Article
- A Comparison of the Effect of Two Doses of Oral Melatonin as Premedication on Orientation Score, Induction Compliance, and Emergency Agitation of Children Undergoing Elective Surgeries: A Double-Blinded Randomized Trial.Anesthesiology research and practice · 2025Article
- Effects of Approved Pharmacological Interventions for Insomnia on Mood Disorders: A Systematic Review.Clinical neuropsychiatry · 2024Review
- Blunted Melatonin Circadian Rhythm in Parkinson's Disease: Express Bewilderment.Neurotoxicity research · 2024Review
- Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.Sleep and biological rhythms · 2024Article
- Modulation of neural circuits by melatonin in neurodegenerative and neuropsychiatric disorders.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Laura PalaginiPsychiatry Division, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Raffaele ManniUnit of Sleep Medicine and Epilepsy, Istituto di Ricovero e Cura a Carattere Scientifico Mondino Foundation, Pavia, Italy.
Eugenio AgugliaDepartment of Experimental and Clinical Medicine, Psychiatric Clinic University Hospital "Gaspare Rodolico", University of Catania, Catania, Italy.
Mario AmoreSection of Psychiatry, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
Roberto BrugnoliDepartment of Neuroscience, Mental Health, and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sant'Andrea University Hospital, Sapienza University, Rome, Italy.
Stéphanie BioulacUniversity Sleep Clinic, Services of Functional Exploration of the Nervous System, University Hospital of Bordeaux, and USR CNRS 3413 SANPSY, University Hospital Pellegrin, University of Bordeaux, Bordeaux, France.
Patrice BourginInstitut des Neurosciences Cellulaires et Intégratives, CNRS-UPR 3212, Strasbourg, France.
Jean-Arthur Micoulaud FranchiUniversity Sleep Clinic, Services of Functional Exploration of the Nervous System, University Hospital of Bordeaux, and USR CNRS 3413 SANPSY, University Hospital Pellegrin, University of Bordeaux, Bordeaux, France.
Paolo GirardiDepartment of Neuroscience, Mental Health, and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sant'Andrea University Hospital, Sapienza University, Rome, Italy.
Luigi GrassiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Régis LopezService de Neurologie, Centre National de Référence Narcolepsie Hypersomnies, Unité des Troubles du Sommeil, Hôpital Gui-de-Chauliac Montpellier, Montpellier, France.
Claudio MencacciDepartment of Neuroscience, Aziende Socio Sanitarie Territoriali Fatebenefratelli Sacco, Milan, Italy.
Giuseppe PlazziDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Julia MaruaniDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat - Claude Bernard, Paris, France.
Antonino MinervinoDepartment of Psychiatry, Italian Society of Psychosomatic Medicine (SIMP), Parma, Italy.
Pierre PhilipUniversity Sleep Clinic, Services of Functional Exploration of the Nervous System, University Hospital of Bordeaux, and USR CNRS 3413 SANPSY, University Hospital Pellegrin, University of Bordeaux, Bordeaux, France.
Sylvie Royant ParolaReseau Morphee Paris, Paris, France.
Isabelle PoirotService de psychiatrie adulte, Hôpital Fontan, CHU de Lille, Lille, France.
Lino NobiliDepartment of Neuroscience (DINOGMI), University of Genoa, Genoa, Italy.
Giovanni BiggioDepartment of Life and Environmental Sciences, Institute of Neuroscience, CNR, University of Cagliari, Cagliari, Italy.
Carmen M SchroderInstitut des Neurosciences Cellulaires et Intégratives, CNRS-UPR 3212, Strasbourg, France.
Pierre A GeoffroyDépartement de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hopital Bichat - Claude Bernard, Paris, France.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
circadian sleep disordersdeliriumdementiaexpert opinioninsomniamelatoninpsychiatric disorders
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.