Evidence map›Paper›PMID 34177583›Full record

ArticleFrontiers in pharmacology2021

AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.

Rui Ye, Cuihong Wang, Pengbo Sun, Shuang Bai, Li Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Article
  3. Lung Transcriptomics Link Emphysema to Barrier Dysfunction and Macrophage Subpopulations.American journal of respiratory and critical care medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Prognostic Biomarkers Based on Proteomic Technology in COPD: A Recent Review.International journal of chronic obstructive pulmonary disease · 2023
    Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rui YeDepartment of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Cuihong WangDepartment of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Pengbo SunDepartment of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Shuang BaiDepartment of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Li ZhaoDepartment of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AGR3airway epithelial barrierCOPDfrequent exacerbatorhuman lung tissue

Identifiers

PMID34177583
PMCPMC8232749
OpenAlexW3167857117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.