Evidence map›Paper›PMID 34177581›Full record

ArticleFrontiers in pharmacology2021

Potential Disease-Modifying Effects of Lithium Carbonate in Niemann-Pick Disease, Type C1.

Shiqian Han, Huiwen Zhang, Mengni Yi, Xiaoqing Liu, Gustavo H B Maegawa, Yunding Zou, Qijun Wang, Dianqing Wu, Zhijia Ye

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Shiqian HanDepartment of Tropical Medicine, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Huiwen ZhangDepartment of Pediatric Endocrinology and Genetics, Xinhua Hospital, Shanghai Institute for Pediatric Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Mengni YiDepartment of Pediatric Endocrinology and Genetics, Xinhua Hospital, Shanghai Institute for Pediatric Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaoqing LiuDepartment of Pediatric Endocrinology and Genetics, Xinhua Hospital, Shanghai Institute for Pediatric Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Gustavo H B MaegawaDepartment of Pediatrics, Genetics and Metabolism, University of Florida, Gainesville, FL, United States.
Yunding ZouDepartment of Hematology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Qijun WangDepartment of Gastroenterology of Ruijin Hospital, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dianqing WuDepartments of Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, United States.
Zhijia YeDepartment of Tropical Medicine, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Army Medical University · CNShanghai Jiao Tong University · CNXinHua Hospital · CNSouthwest Hospital · CNUniversity of Florida · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Signaling mechanisms and functions related to patho-physiology of vascular, lung and blood systemsR35HL135805 · NHLBI · YALE UNIVERSITY · PI WU, DIANQING · 2017 to 2023
$6.4M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R35 HL135805
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

7-ketocholesterolclinical triallithiumniemann-pick diseaseNNSS

Identifiers

PMID34177581
PMCPMC8220070
OpenAlexW3172183572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.