Evidence map›Paper›PMID 34177431›Full record

ArticleMolecular syndromology2021

Potential Pitfalls in Pre-implantation Genetic Diagnosis in a Patient with Tuberous Sclerosis and Isolated Mosaicism for a

Kristin M Ikeda, Andrew A House, Dervla M Connaughton, Stephen E Pautler, Victoria Mok Siu, Michelle-Lee Jones

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular syndromology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kristin M IkedaDepartment of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada.
Andrew A HouseSchulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Dervla M ConnaughtonSchulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Stephen E PautlerSchulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Victoria Mok SiuSchulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Michelle-Lee JonesDepartment of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that displays a wide spectrum of clinical manifestations, often affecting multiple organs including the kidneys, brain, lungs, and skin. A pathogenic mutation in either the

Indexed as

Genetic counsellingMosacismTuberous sclerosis

Identifiers

PMID34177431
PMCPMC8215990
OpenAlexW3140611619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.