Evidence map›Paper›PMID 34177371›Full record

ArticleJournal of medical biochemistry2021

Thiol/disulfide homeostasis impaired in patients with primary Sjögren's syndrome.

Cakmak Nuray Yilmaz, Emin Gemcioglu, Salih Baser, Sükran Erten, Ozcan Erel

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Article in Journal of medical biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cakmak Nuray YilmazAnkara City Hospital, Department of Internal Medicine, Ankara, Turkey.
Emin GemciogluAnkara City Hospital, Department of Internal Medicine, Ankara, Turkey.
Salih BaserYıldırım Beyazıt University, Ankara City Hospital, Department of Internal Medicine, Ankara, Turkey.
Sükran ErtenYıldırım Beyazıt University, Ankara City Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey.
Ozcan ErelYıldırım Beyazıt University, Ankara City Hospital, Department of Biochemistry, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary Sjögren's syndrome (pSS) is a disease associated with the overexpression of proinflammatory cytokines, and oxidative stress is one of the factors responsible for its etiopathogenesis. This study aimed to investigate the thiol/disulphide homeostasis in pSS patients.

methodsThe study included 68 pSS patients and 69 healthy controls. Thiol/disulphide homeostasis (total thiol, native thiol, and disulphide levels) was measured using the automatic spectrophotometric method developed by Erel and Neselioglu, and the results of the 2 groups were compared.

resultsThe gender and age distributions of the pSS and control groups were similar (

conclusionsIt was concluded that the thiol/disulphide balance shifted towards disulphide in patients with pSS.

Indexed as

oxidative stressprimary Sjögren's syndromethiol/disulphide homeostasis

Identifiers

PMID34177371
PMCPMC8199498

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