ArticleJournal of medical biochemistry2021
Stability of hematological analytes during 48 hours storage at three temperatures using Cell-Dyn hematology analyzer.
Article in Journal of medical biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Efficacy and Safety of Vortexing as a Practical Solution for Resolving Platelet Clumping in hematology laboratories.International journal of laboratory hematology · 2026Article
- Psychophysical stress during a 24 h dive: A case study of an older male diver.Physiological reports · 2026Article
- Time stability of Intensive Care Infection Score (ICIS) as a cellular hematology biomarker for infection in critically ill patients.Scientific reports · 2026Article
- Effects of Botanical Supplementation on Benzene-Induced Hematological, Histopathological, and Molecular Alterations in Rats : Short title: Botanical Supplementation In Benzene-Induced Leukemia Rats.Galen medical journal · 2026Article
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- Stability testing of HPCs and MNCs from apheresis products.Immunobiology · 2025Article
- Impact of pre-analytical variables - temperature, agitation, storage duration, and blood-to-anticoagulant ratio - on complete blood count test reliability.Medicine and pharmacy reports · 2025Article
- Effect of Anesthesia on Hematologic Parameters of Female Domestic Swine (Sus scrofa domestica).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- A comparative study of blood cell count in four automated hematology analyzers: An evaluation of the impact of preanalytical factors.PloS one · 2024Article
- Red blood cell distribution width: the importance of preanalytical and analytical phase variables.Wiener klinische Wochenschrift · 2023Article
- Measures of Oxidative Status Markers in Relation to Age, Sex, and Season in Sick and Healthy Captive Asian Elephants in Thailand.Animals : an open access journal from MDPI · 2023Article
- Article
- Analyte stability, instrumentation, and the red blood cell distribution width: comments on "Red blood cell distribution width and tumor necrosis factor‑α for the early prediction of coronary artery lesion in Kawasaki disease: a retrospective study". Eur J Pediatr. 2021 Sep 7.doi: 10.1007/s00431-021-04,252-3.European journal of pediatrics · 2022Article
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Abstract
backgroundThe complete blood count (CBC) with differential leukocyte count (DLC) is one of the most common tests requested by physicians. The results of this test are affected by storage temperature and time of incubation. This study was designed to evaluate the stability of hematologic parameters in blood specimens stored for 48 h at three temperatures.
methodsK2-EDTA - blood was collected from 22 healthy adults. The CBC was performed using a hematology analyser immediately; 0 time point and at 4, 8, 12, 16, 20, 24, and 48 h after storage at 4 °C, 10 °C or 23 °C. Changes in values of CBC parameters from the 0 time point were determined and reported as % of the initial value.
resultsRed blood cells, platelet, hemoglobin, and mean corpuscular hemoglobin were found stable during 48 h storage at 4 °C, 10 °C or 23 °C. Hematocrite and mean corpuscular volume increased, while white blood cells decreased at 48 h when stored at 23 °C. Lymphocytes, neutrophils, eosinophils, and basophils showed significant differences after 12 h of storage at 23 °C.
conclusionsRed blood cells, platelet, hemoglobin, and mean corpuscular hemoglobin are the only suitable parameters without refrigeration during 24 h storage. When CBC and DLC are performed, 4 °C can be recommended as the most suitable storage temperature for 12 h storage.
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