Evidence map›Paper›PMID 34177367›Full record

ArticleJournal of medical biochemistry2021

IGFBP-4: A promising biomarker for lung cancer.

Savas Irem Nur, Akin Ozturk, Murat Kavas, Ismet Bulut, Sumeyye Alparslan, Eroglu Selma Aydogan, Baytemir Cansel Atinkaya, Murat Kolay, Abdurrahman Coskun

Open access · diamondAbstract read
In one paragraph

Article in Journal of medical biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. IGF Pathway Components as Potential Biomarkers in Gastric Cancer.International journal of molecular sciences · 2025
    Article
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  11. Effects of Obesity and Calorie Restriction on Cancer Development.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Savas Irem NurAcibadem Mehmet Ali Aydınlar University, School of Medicine, Department of Biochemistry, Istanbul, Turkey.
Akin OzturkUniversity of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Medical Oncology, Istanbul, Turkey.
Murat KavasUniversity of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Chest Disease, Istanbul, Turkey.
Ismet BulutUniversity of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Allergy and Immunology, Istanbul, Turkey.
Sumeyye AlparslanUniversity of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Chest Disease, Istanbul, Turkey.
Eroglu Selma AydoganUniversity of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Chest Disease, Istanbul, Turkey.
Baytemir Cansel AtinkayaUniversity of Health Sciences, Istanbul Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Thoracic Surgery, Istanbul, Turkey.
Murat KolayAcibadem Labmed Clinical Laboratories, Department of Biochemistry, Istanbul, Turkey.
Abdurrahman CoskunAcibadem Mehmet Ali Aydınlar University, School of Medicine, Department of Biochemistry, Istanbul, Turkey.
Sağlık Bilimleri Üniversitesi · TRAcıbadem Adana Hospital · TRKent Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkersIGF-1IGFBP-4lung cancerPAPP-A

Identifiers

PMID34177367
PMCPMC8199439
OpenAlexW3171994497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.