Evidence map›Paper›PMID 34177288›Full record

ArticleThe Eurasian journal of medicine2021

The Effect of Polypharmacy on the Charlson Comorbidity Index and Katz Index in Aging People with and without Diabetes Mellitus.

Gulcin Sahingoz Erdal, Hakan Kocoglu, Faruk Karandere, Pinar Kasapoglu, Nilgun Isiksacan, Mehmet Hursitoglu

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Article in The Eurasian journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gulcin Sahingoz ErdalDepartment of Internal Medicine, Bakırköy Dr Sadi Konuk Training And Research Hospital, İstanbul, Turkey.ORCID https://orcid.org/0000-0001-5815-5847
Hakan KocogluDepartment of Internal Medicine, Bakırköy Dr Sadi Konuk Training And Research Hospital, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-9208-2693
Faruk KarandereDepartment of Internal Medicine, Bakırköy Dr Sadi Konuk Training And Research Hospital, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-7423-0170
Pinar KasapogluDepartment of Biochemistry, Bakırköy Dr Sadi Konuk Training And Research Hospital, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-1703-2204
Nilgun IsiksacanDepartment of Biochemistry, Bakırköy Dr Sadi Konuk Training And Research Hospital, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-0230-6500
Mehmet HursitogluDepartment of Internal Medicine, Bakırköy Dr Sadi Konuk Training And Research Hospital, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-9062-118X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe prevalence of diabetes mellitus is growing worldwide, as well as in the aging population, and its comorbidity and mortality rates are higher in aging people than they are in young people. It has been observed that the number of drugs used increases in aging patients, especially in diabetic patients. This study aimed to investigate the relationship between polypharmacy and modified Charlson Comorbidity Index (CCI) and Katz Index of Independence in Activities of Daily Living (Katz ADL) scores in aging diabetic and non-diabetic patients. MATERIALS AND

methodsThis prospective study included 184 diabetic and 62 non-diabetic subjects who were ≥65 years old. Comorbidity was determined with CCI, and dependency on daily basic activities was assessed with Katz ADL.

resultsCCI and the number of drugs were significantly higher in diabetic groups (

conclusionWe found an increase in the number of drugs taken by the aging patients, positively correlated with the CCI score. The increase in the number of drugs used is closely related to the insufficiency in daily life activity and comorbidity, and this predicts 10-year survival. Patients should be directed to special centers or physicians who will be scheduled for multidisciplinary treatment for the prevention of polypharmacy, especially in the aging.

Indexed as

AgingDiabetes mellitusIndexPolypharmacy

Identifiers

PMID34177288
PMCPMC8184046

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.