Evidence map›Paper›PMID 34176992›Full record

ArticleComputer methods in applied mechanics and engineering2021

Model order reduction of flow based on a modular geometrical approximation of blood vessels.

Luca Pegolotti, Martin R Pfaller, Alison L Marsden, Simone Deparis

Abstract read
In one paragraph

Article in Computer methods in applied mechanics and engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Automated generation of 0D and 1D reduced-order models of patient-specific blood flow.International journal for numerical methods in biomedical engineering · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luca PegolottiSCI-SB-SD, Institute of Mathematics, École Polytechnique Fédérale de Lausanne, Station 8, EPFL, CH-1015 Lausanne, Switzerland.
Martin R PfallerDepartment of Pediatrics (Cardiology), Bioengineering, Stanford University, Clark Center E1.3, 318 Campus Drive, Stanford, CA 94305, USA.
Alison L MarsdenDepartment of Pediatrics (Cardiology), Bioengineering, Stanford University, Clark Center E1.3, 318 Campus Drive, Stanford, CA 94305, USA.
Simone DeparisSCI-SB-SD, Institute of Mathematics, École Polytechnique Fédérale de Lausanne, Station 8, EPFL, CH-1015 Lausanne, Switzerland.

Funding

SCH: INT: A Virtual Surgery Simulator to Accelerate Medical Training in Cardiovascular Disease R01EB029362 · NIBIB · STANFORD UNIVERSITY · PI MARSDEN, ALISON L · 2019 to 2022
$1.4M
Automated data curation to ensure model credibility in the Vascular Model RepositoryR01LM013120 · NLM · STANFORD UNIVERSITY · PI MARSDEN, ALISON L · 2019 to 2021
$1.0M
NIBIB NIH HHS R01 EB029362NLM NIH HHS R01 LM013120
6 · The paper itself

Abstract

We are interested in a reduced order method for the efficient simulation of blood flow in arteries. The blood dynamics is modeled by means of the incompressible Navier-Stokes equations. Our algorithm is based on an approximated domain-decomposition of the target geometry into a number of subdomains obtained from the parametrized deformation of geometrical building blocks (e.g., straight tubes and model bifurcations). On each of these building blocks, we build a set of spectral functions by Proper Orthogonal Decomposition of a large number of snapshots of finite element solutions (offline phase). The global solution of the Navier-Stokes equations on a target geometry is then found by coupling linear combinations of these local basis functions by means of spectral Lagrange multipliers (online phase). Being that the number of reduced degrees of freedom is considerably smaller than their finite element counterpart, this approach allows us to significantly decrease the size of the linear system to be solved in each iteration of the Newton-Raphson algorithm. We achieve large speedups with respect to the full order simulation (in our numerical experiments, the gain is at least of one order of magnitude and grows inversely with respect to the reduced basis size), whilst still retaining satisfactory accuracy for most cardiovascular simulations.

Indexed as

Cardiovascular simulationsDomain-decompositionModel order reductionReduced basis method

Identifiers

PMID34176992
PMCPMC8232546

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.