Evidence map›Paper›PMID 34176763›Full record

ArticleSeminars in fetal & neonatal medicine2021

Ethical considerations in the care of encephalopathic neonates treated with therapeutic hypothermia.

Monica E Lemmon, Courtney J Wusthoff, Renee D Boss, Lisa Anne Rasmussen, Newborn Brain Society Guidelines and Publications Committee

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Seminars in fetal & neonatal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Monica E LemmonDivision of Pediatric Neurology and Developmental Medicine, Departments of Pediatrics and Population Health Sciences, Duke University School of Medicine, DUMC 3936, Durham, NC, 27710, USA. Electronic address: monica.lemmon@duke.edu.
Courtney J WusthoffDepartments of Neurology and Pediatrics, Stanford University, Stanford, 750 Welch Road, Suite 317, Palo Alto, CA, 94304, USA. Electronic address: wusthoff@stanford.edu.
Renee D BossDivision of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Johns Hopkins Berman Institute of Bioethics, 200 N. Wolfe St, Suite 2019, Baltimore, MD, 21287, United States. Electronic address: rboss1@jhmi.edu.
Lisa Anne RasmussenDivision of Palliative Care, Department of Family Medicine, Department of Neurology, Department of Pediatrics, Larner College of Medicine, University of Vermont, UVM Medical Center Palliative Care, 111 Colchester Avenue, Main Campus, Smith 262, Burlington, VT, 05401-1473, USA. Electronic address: lisaanne.rasmussen@uvmhealth.org.
Newborn Brain Society Guidelines and Publications Committee
Duke University · USJohns Hopkins Berman Institute of Bioethics · USStanford University · USUniversity of Vermont Medical Center · US

Funding

Decision Making for Infants with Neurologic ConditionsK23NS116453 · NINDS · DUKE UNIVERSITY · PI LEMMON, MONICA · 2020 to 2024
$942k
NINDS NIH HHS K23 NS116453
6 · The paper itself

Abstract

Engaging with ethical issues is central to the management of neonatal encephalopathy (NE). As treatment for these neonates evolves, new ethical issues will arise and many existing challenges will remain. We highlight three key ethical issues that arise in the care of neonates with NE treated with therapeutic hypothermia: facilitating shared decision making, understanding futility, and defining the boundaries between standard of care and research. Awareness of these issues will help clinicians counsel families in light of evolving treatments and outcomes.

Indexed as

Brain DiseasesHypothermia, InducedHumansInfant, NewbornDecision makingFutilityPrognosis

Identifiers

PMID34176763
PMCPMC8627487
OpenAlexW3166889756

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.