Evidence map›Paper›PMID 34176483›Full record

ArticleBMC immunology2021

Assessment of CD27 expression on T-cells as a diagnostic and therapeutic tool for patients with smear-negative pulmonary tuberculosis.

Feifan Xu, Haiyun Zhang, Xiaoyan Si, Junlin Chen, Yuhao Chen, Xiaopeng Cui, Yongwei Qin

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Feifan XuDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong, 226001, China.
Haiyun Zhang *Department of Clinical Laboratory, The Sixth People's Hospital of Nantong, Nantong, 226011, China.
Xiaoyan Si *Department of Clinical Laboratory, The Sixth People's Hospital of Nantong, Nantong, 226011, China.
Junlin ChenDepartment of Tuberculosis, The Sixth People's Hospital of Nantong, Nantong, 226011, China.
Yuhao ChenDepartment of General Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Xiaopeng CuiDepartment of General Surgery, Affiliated Hospital of Nantong University, Nantong, China. cuixiaopeng2000@163.com.
Yongwei QinDepartment of Pathogen Biology, School of Medicine, Nantong University, Nantong, 226001, China. yw_qin@foxmail.com.ORCID 0000-0003-2638-6960
Nantong University · CN

Funding

Nantong Science and Technology Bureau JC2018069
6 · The paper itself

Abstract

backgroundThere is a global focus on illness diagnosis in smear-negative and latent tuberculosis infectious populations (SN-TB and LTBI). CD27 has been suggested to play a direct role in active TB. Little is known about smear-negative individuals. Here, we tried to investigate whether it has a role in smear-negative populations. The expression of CD27 and MTB-specific CD27 in CD4

resultsWe observed that the percentages of "CD27

conclusionThe present results demonstrated that the percentage of "CD27

Indexed as

AdultCD4-Positive T-LymphocytesFemaleFlow CytometryHumansInterferon-gammaLatent TuberculosisLymphocyte CountMaleMiddle AgedMycobacterium tuberculosisROC CurveSensitivity and SpecificityTuberculosis, PulmonaryTumor Necrosis Factor Receptor Superfamily, Member 7Interferon-gammaTumor Necrosis Factor Receptor Superfamily, Member 7CD27DiagnosisSmear-negative pulmonary tuberculosisTherapy

Identifiers

PMID34176483
PMCPMC8237462
OpenAlexW3175732773

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.