Evidence map›Paper›PMID 34176350›Full record

ArticleScience progress

Protective effects of baicalin on caerulein-induced AR42J pancreatic acinar cells by attenuating oxidative stress through miR-136-5p downregulation.

Zhu-Fen Zhao, Ye Zhang, Yang Sun, Chun-Hai Zhang, Ming-Wei Liu

Open access · diamondAbstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. The Role of MicroRNAs in Pancreatitis Development and Progression.International journal of molecular sciences · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhu-Fen ZhaoDepartment of Emergency Medicine, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Ye ZhangDepartment of Traditional Chinese Medicine, The Third People's Hospital of Yunnan Province, Kunming, China.
Yang SunDepartment of Nephrology, The Sixth Affiliated Hospital of Kunming Medical University, Yuxi, Yunnan, China.
Chun-Hai ZhangDepartment of Emergency Medicine, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Ming-Wei LiuDepartment of Emergency Medicine, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.ORCID 0000-0002-3728-2350
Kunming Medical University · CNThird People's Hospital of Yunnan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baicalin, the main active component of

Indexed as

MicroRNAsPancreatitisAcinar CellsAcute DiseaseApoptosisCeruletideDown-RegulationFlavonoidsHumansOxidative StressReactive Oxygen SpeciesSuperoxide Dismutase-1baicalinCeruletideFlavonoidsMicroRNAsMIRN136 microRNA, humanReactive Oxygen SpeciesSuperoxide Dismutase-1acute pancreatitisAR42J acinar cellsBaicalinmiR-136-5poxidative stresssuperoxide dismutase 1

Identifiers

PMID34176350
PMCPMC10305831
OpenAlexW3175462756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.