Evidence map›Paper›PMID 34176050›Full record

ArticleLa Radiologia medica2021

The impact of TI-RADS in detecting thyroid malignancies: a prospective study.

Esra Soyer Güldoğan, Onur Ergun, Tuğba Taşkın Türkmenoğlu, Kerim Bora Yılmaz, Tuba Akdağ, Serra Özbal Güneş, Hasan Ali Durmaz, Baki Hekimoğlu

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Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  11. Imaging Assessment of Interval Metastasis from Melanoma.Journal of personalized medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Esra Soyer GüldoğanDepartment of Radiology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey. esra_soyer@hotmail.com.ORCID http://orcid.org/0000-0002-9251-5241
Onur ErgunDepartment of Radiology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Tuğba Taşkın TürkmenoğluDepartment of Pathology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Kerim Bora YılmazDepartment of General Surgery, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Tuba AkdağDepartment of Radiology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Serra Özbal GüneşDepartment of Radiology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Hasan Ali DurmazDepartment of Radiology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Baki HekimoğluDepartment of Radiology, Health Sciences University Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThyroid ultrasonography (US) is the first-step noninvasive and easily accessible diagnostic method widely used in the detection and characterization of nodular thyroid disease. We aimed to develop a TI-RADS, which is easy to apply and only relies on the counting of suspicious criteria. In order to measure the reliability of the system, we investigated its correlation with fine needle aspiration biopsy (FNAB) and post-surgery histological results. MATERIALS AND

methodsIn this prospective study, 242 patients who had undergone FNAB with simultaneous cytopathologist in the radiology department between April and August 2016 were analyzed. Before FNAB, the thyroid gland was re-evaluated with US, and TI-RADS classification was made. Demographic characteristics, family thyroid cancer history and radiotherapy history to the neck region were noted.

resultsOf the 242 patients, 17.3% were male (42 males/200 females). US-guided FNAB was applied to all patients. Mean age was 50 ± 13 years (min: 19, max: 82). Both FNAB and final post-surgery histology results showed that sex and age were not statistically significantly associated with malignancy (p = 0.193) TI-RADS criteria and FNAB results revealed a statistically significant association between irregular contours, the state of anteroposterior diameter being longer than transverse diameter, microcalcifications, marked hypoechogenicity, and malignancy (p < 0,05). Thirty patients were TI-RADS ≥ 4, 206 patients were TI-RADS ≤ 3 and there was a significant correlation between TI-RADS and Bethesda classification (p = 0.001). In addition, statistically significant associations were found between malignancy and family history of thyroid cancer (p = 0.035) and radiotherapy history to the neck region (p = 0.01).

conclusionTI-RADS system after nodule identification is based only on the counting of suspicious criteria. It will be safe and effective to recommend follow-up with low score TI-RADS, benign characters and insufficient FNAB results, and thus, unnecessary thyroidectomy operations will be prevented. It will be easier for surgeons to recommend surgery and persuade the patients for it when patients have high TI-RADS scores. TI-RADS has high power in detecting malignancy by recommending biopsy of suspicious nodules.

Indexed as

AdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesRadiology Information SystemsReproducibility of ResultsThyroid GlandThyroid NeoplasmsUltrasonographyYoung AdultFine needle aspiration biopsyThyroid nodulesTI-RADSUltrasonography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.