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ArticleArchives of osteoporosis2021

The Indian Society for Bone and Mineral Research (ISBMR) position statement for the diagnosis and treatment of osteoporosis in adults.

Sanjay K Bhadada, Manoj Chadha, Usha Sriram, Rimesh Pal, Thomas V Paul, Rajesh Khadgawat, Ameya Joshi, Beena Bansal, Nitin Kapoor, Anshita Aggarwal and 10 more

Abstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
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  5. Article
  6. Article
  7. Article
  8. Prevalence of Osteonecrosis in Survivors of Childhood Acute Lymphoblastic Leukaemia of Indian Ethnicity Treated with BFM Protocol.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  9. Cost-effectiveness of FRAX®-based intervention thresholds for management of osteoporosis in Indian women: a Markov microsimulation model analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
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  14. Article
  15. Article
  16. Review
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  18. DEXA and Imaging in Osteoporosis.Indian journal of orthopaedics · 2023
    Review
  19. Diabetes and Osteoporosis.Indian journal of orthopaedics · 2023
    Review
  20. Non-biological Antiresorptive: Bisphosphonates.Indian journal of orthopaedics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 2 countries.

Sanjay K BhadadaDepartment of Endocrinology, Post Graduate Institute Of Medical Education and Research, Chandigarh, 160012, India. bhadadask@rediffmail.com.
Manoj ChadhaDepartment of Endocrinology, Parmanand Deepchand Hinduja Hospital, Mumbai, 400016, India.
Usha SriramEndocrinology and Diabetology Division, Voluntary Health Services Hospital, Chennai, 600020, India.
Rimesh PalDepartment of Endocrinology, Post Graduate Institute Of Medical Education and Research, Chandigarh, 160012, India.
Thomas V PaulDepartment of Endocrinology, Christian Medical College, Vellore, 632002, India.
Rajesh KhadgawatDepartment of Endocrinology, All India Institute Of Medical Sciences, New Delhi, 110023, India.
Ameya JoshiEndocrinology Division, Bhaktivedanta Hospital, Thane, 401107, India.
Beena BansalEndocrinology and Diabetes Division, Door to Care, Gurgaon, 122018, India.
Nitin KapoorDepartment of Endocrinology, Christian Medical College, Vellore, 632002, India.
Anshita AggarwalDepartment of Endocrinology, Dr. Ram Manohar Lohia Hospital, New Delhi, 110001, India.
Mahendra K GargDepartment of Endocrinology, All India Institute Of Medical Sciences, Jodhpur, 342001, India.
Nikhil TandonDepartment of Endocrinology, All India Institute Of Medical Sciences, New Delhi, 110023, India.
Sushil GuptaDepartment of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India.
Narendra KotwalDepartment of Endocrinology, Army Hospital Research & Referral, New Delhi, 110010, India.
Shriraam MahadevanEndocrinology Division, Sri Ramachandra Medical Center, Chennai, 600116, India.
Satinath MukhopadhyayDepartment of Endocrinology, Institute of Post-Graduate Medical Education and Research, Kolkata, 700020, India.
Soham MukherjeeDepartment of Endocrinology, Post Graduate Institute Of Medical Education and Research, Chandigarh, 160012, India.
Subhash C KukrejaDepartment of Medicine, University of Illinois, Chicago, IL, 60612, USA.
Sudhaker D RaoDepartment of Internal Medicine, Division of Endocrinology, Diabetes and Bone & Mineral Disorders, Henry Ford, Health System, Detroit, MI, 48202, USA.
Ambrish MithalEndocrinology and Diabetes Division, Max Healthcare, New Delhi, 110017, India. ambrishmithal@hotmail.com.
Post Graduate Institute of Medical Education and Research · INAll India Institute of Medical Sciences · INChristian Medical College & Hospital · INAll India Institute of Medical Sciences Jodhpur · INArmy Hospital Research and Referral · INAtal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital · INBhaktivedanta Hospital & Research Institute · INHenry Ford Health System · USInstitute of Post Graduate Medical Education and Research · INMax Healthcare · INP. D. Hinduja Hospital and Medical Research Centre · INSanjay Gandhi Post Graduate Institute of Medical Sciences · INSri Ramachandra Medical Centre · INUniversity of Illinois Chicago · USVoluntary Health Services Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Indian Society for Bone and Mineral Research (ISBMR) has herein drafted clinical practice guidelines for the diagnosis and management of osteoporosis for the people of India. Implementation of the position statement in clinical practice is expected to improve the overall care of patients with osteoporosis in India. PURPOSE: In India, osteoporosis is a major public health problem. However, in the absence of any robust regional guidelines, the screening, treatment, and follow-up of patients with osteoporosis are lagging behind in the country.

methodsThe Indian Society for Bone and Mineral Research (ISBMR), which is a multidisciplinary group of physicians, researchers, dietitians, and epidemiologists and who study bone and related tissues, in their annual meeting, drafted the guidelines for the diagnosis and management of osteoporosis that would be appropriate in a resource constraint setting like India.

resultsDiagnosis of osteoporosis can be made in a patient with minimal trauma fracture without the aid of any other diagnostic tools. In others, bone mineral density measured by dual-energy X-ray absorptiometry remains the modality of choice. Data indicates that osteoporotic fractures occur at an earlier age in Indians than in the West; hence, screening for osteoporosis should begin at an earlier age. FRAX can be used for fracture risk estimation; however, it may underestimate the risk of future fractures in our population and still needs validation. Maintaining optimum serum 25-hydroxyvitamin D levels is essential, which, in most cases, would require regular vitamin D supplementation. Pharmacotherapy should be guided by the presence/absence of vertebral/hip fractures or the severity of risk based on clinical factors, although bisphosphonates remain the first choice in most cases. Regular follow-up is essential to ensure adherence and response to therapy.

conclusionsImplementation of the position statement in clinical practice is expected to improve the overall care of patients with osteoporosis in India.

Indexed as

OsteoporosisOsteoporotic FracturesAbsorptiometry, PhotonAdultBone DensityHumansMineralsRisk FactorsMineralsFracture preventionGuidelinesIndiaISBMROsteoporosis

Identifiers

PMID34176015
OpenAlexW3175730563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.