Evidence map›Paper›PMID 34175990›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2022

Varus alignment of the tibial component up to seven degrees is not associated with poor long-term outcomes in a neutrally aligned total knee arthroplasty.

Francisco Antonio Miralles-Muñoz, Marta Rubio-Morales, Laiz Bello-Tejada, Santiago González-Parreño, Alejandro Lizaur-Utrilla, Carolina Alonso-Montero

Registry-linked trialAbstract read
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In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05944679 (Prospective Randomized Study of the Clinical Utility to Follow-up Radiographs During the First Year of Knee Replacement Surgery), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05944679 nacompletednot on this map

Prospective Randomized Study of the Clinical Utility to Follow-up Radiographs During the First Year of Knee Replacement Surgery

TypeinterventionalSponsorCorporacion Parc TauliRan2022 to 2024Enrolled200ConditionsProsthetic Knee SurgeryArmsNo Xray, Xray
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Francisco Antonio Miralles-MuñozDepartment of Orthopaedic Surgery, University Hospital of Elda, Ctra Elda-Sax s/n, 03600, Elda, Alicante, Spain. fr_miralles@hotmail.com.ORCID http://orcid.org/0000-0002-3032-1492
Marta Rubio-MoralesDepartment of Orthopaedic Surgery, University Hospital of Elda, Ctra Elda-Sax s/n, 03600, Elda, Alicante, Spain.
Laiz Bello-TejadaDepartment of Orthopaedic Surgery, University Hospital of Elda, Ctra Elda-Sax s/n, 03600, Elda, Alicante, Spain.
Santiago González-ParreñoDepartment of Orthopaedic Surgery, University Hospital of Elda, Ctra Elda-Sax s/n, 03600, Elda, Alicante, Spain.
Alejandro Lizaur-UtrillaDepartment of Orthopaedic Surgery, University Hospital of Elda, Ctra Elda-Sax s/n, 03600, Elda, Alicante, Spain.ORCID http://orcid.org/0000-0003-4798-2702
Carolina Alonso-MonteroFaculty of Medicine, Department of Traumatology and Orthopaedics, Miguel Hernandez University, Elche, Alicante, Spain.
Hospital General de Elda · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this retrospective study was to evaluate the effect of varus alignment of the tibial component on the outcomes with a minimum follow-up of 10 years. The hypothesis was that varus alignment of the tibial component might not affect the outcomes and survival of a neutrally aligned primary TKA.

methodsA matched case-control study was designed between 66 patients with varus alignment of the tibial component and 66 with neutral alignment with a minimum follow-up of 10 years. Functional outcome was assessed with the knee surgery scores (KSS) and reduced Western Ontario and MacMaster Universities questionnaire (WOMAC). Patient satisfaction was evaluated by a 0-10 visual analog scale. Radiological evaluation was performed at early postoperative and at final follow-up.

resultsThe mean follow-up was 11.9 (SD 2.6) years for both groups. The mean postoperative proximal tibial angle in the varus group was 85.0° (SD 0.9) and 88.8° (SD 0.9) in control group. At the final follow-up, there were no significant differences in KSS, WOMAC, range of motion or patient satisfaction. There were no differences in the coronal anatomical alignment of the TKA between groups. Revision of TKA was performed in four knees in the varus group, and one in control group, due to aseptic loosening of the tibial component in all cases. TKA survival at 10 years was not significantly different between groups.

conclusionThe alignment of the tibial component up to 7° varus did not negatively affect implant survival, patient satisfaction, and function of a well-aligned TKA, with a minimum postoperative follow-up of 10 years. LEVEL OF EVIDENCE: III.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisOsteoarthritis, KneeCase-Control StudiesHumansKnee JointRetrospective StudiesOutcomeSurvivalTibial componentTotal knee arthroplastyTotal knee replacementVarus alignment

Identifiers

PMID34175990
OpenAlexW3176056899

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.