Evidence map›Paper›PMID 34175754›Full record

ArticleSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2021

Combining subsidiary and synchronous approaches for concurrent spectrofluorimetric assurance of lopinavir and ritonavir in tablets utilized in convention for treatment of coronavirus infection (COVID-19) and biological fluids.

Hesham Salem, Ebtihal Samir, Amany Abdelaziz, Mahmoud Alaa El-Din, Mahmoud Abdelgaleel, Dina Zein, Hoda Madian

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hesham SalemPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt. Electronic address: hesham.salem@deraya.edu.eg.
Ebtihal SamirPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt.
Amany AbdelazizPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt.
Mahmoud Alaa El-DinPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt.
Mahmoud AbdelgaleelPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt.
Dina ZeinPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt.
Hoda MadianPharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt.
Deraya University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this think about, assurance of lopinavir and ritonavir down to organic concentration level has been carried out. The assurance is based on expanding the selectivity of the spectrofluorimetric procedure by combining both subordinate and synchronous spectrofluorimetric approaches, which allow effective estimation of lopinavir at 248.8 nm and ritonavir at 300.1 nm within the nearness of each other at Δλ of 60 nm. Worldwide Conference on Harmonization approval rules were taken after to completely approve the strategy, and linearity was gotten for the two drugs over the extend of 0.4-2.4 µg mL

Indexed as

Coronavirus InfectionsCOVID-19 Drug TreatmentDrug CombinationsHumansLopinavirRitonavirSARS-CoV-2Spectrometry, FluorescenceTabletsDrug CombinationsLopinavirRitonavirTabletsCOVID-19Fluorescence spectroscopyLopinavirRitonavirSpiked human plasmaSynchronous

Identifiers

PMID34175754
PMCPMC9760120
OpenAlexW3168311305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.