ReviewDiagnostic microbiology and infectious disease2021
Pooled Testing Strategies for SARS-CoV-2 diagnosis: A comprehensive review.
Review in Diagnostic microbiology and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Validation of sample pooling for high-throughput RT-qPCR subtyping of avian influenza A(H5).Microbiology spectrum · 2026Article
- Optimal pooling strategies for respiratory virus testing: A comparative cost-effectiveness analysis.PLOS global public health · 2026Article
- Performance Evaluation of Nasopharyngeal Swab Pooling to Improve SARS-CoV-2 Testing Capacity via Closed Real-Time RT‒PCR Assays.Infection and drug resistance · 2026Article
- Surveillance of zoonotic respiratory viral infections in animal farms: a model project with a focus on One Health approach-A study protocol.Frontiers in public health · 2026Article
- A pooled testing strategy for enterovirus D68 to facilitate local, resource-conserving surveillance.Diagnostic microbiology and infectious disease · 2025Article
- Optimizing surveillance: feasibility of pooled sample testing for bovine alphaherpesvirus 1 detection by real-time PCR.Virusdisease · 2025Article
- Implementation of pooled testing to increase access to routine viral load monitoring for people living with HIV on antiretroviral therapy.Scientific reports · 2025Article
- Aggregating multiple test results to improve medical decision-making.PLoS computational biology · 2025Article
- Novel sampling strategy for regular nucleic acid testing in low risk areas during epidemics.Scientific reports · 2024Article
- Innovation bundles and platforms - a qualitative analysis of health system responses to the COVID-19 pandemic.BMC health services research · 2024Article
- Strategies for Increasing the Throughput of Genetic Screening: Lessons Learned from the COVID-19 Pandemic within a University Community.Biotech (Basel (Switzerland)) · 2024Article
- Clinical performance of AI-integrated risk assessment pooling reveals cost savings even at high prevalence of COVID-19.Scientific reports · 2024Article
- Development and evaluation of three automated media pooling and molecular diagnostic systems for the detection of SARS-CoV-2.Microbiology spectrum · 2024Article
- Transdisciplinary research before, during and after COVID-19 vaccination in Chile: a virtuoso collaboration with future perspectives.Frontiers in public health · 2024Review
- Expanding molecular diagnostic coverage for tuberculosis by combining computer-aided chest radiography and sputum specimen pooling: a modeling study from four high-burden countries.BMC global and public health · 2024Article
- Flexible upscaling of laboratory PCR testing capacity at the Robert Koch Institute during the SARS-CoV-2 pandemic.Virology journal · 2023Article
- Advances in molecular infectious diseases testing in the time of COVID-19.Clinical biochemistry · 2023Review
- Dorfman pooling enhances SARS-CoV-2 large-scale community testing efficiency.PLOS global public health · 2023Article
- Fluorescence spectrophotometry for COVID-19 determination in clinical swab samples.Arabian journal of chemistry · 2022Article
- Laboratory Diagnosis for SARS-CoV-2 Infection.Infectious disease clinics of North America · 2022Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS-CoV-2 has surged across the globe causing the ongoing COVID-19 pandemic. Systematic testing to facilitate index case isolation and contact tracing is needed for efficient containment of viral spread. The major bottleneck in leveraging testing capacity has been the lack of diagnostic resources. Pooled testing is a potential approach that could reduce cost and usage of test kits. This method involves pooling individual samples and testing them 'en bloc'. Only if the pool tests positive, retesting of individual samples is performed. Upon reviewing recent articles on this strategy employed in various SARS-CoV-2 testing scenarios, we found substantial diversity emphasizing the requirement of a common protocol. In this article, we review various theoretically simulated and clinically validated pooled testing models and propose practical guidelines on applying this strategy for large scale screening. If implemented properly, the proposed approach could contribute to proper utilization of testing resources and flattening of infection curve.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.