Evidence map›Paper›PMID 34175521›Full record

ReviewCurrent opinion in neurobiology2021

From synapse to network: models of information storage and retrieval in neural circuits.

Johnatan Aljadeff, Maxwell Gillett, Ulises Pereira Obilinovic, Nicolas Brunel

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. The Dynamicist Landscape.Topics in cognitive science · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Johnatan AljadeffNeurobiology Section, Division of Biological Sciences, UC San Diego, USA.
Maxwell GillettDepartment of Neurobiology, Duke University, USA.
Ulises Pereira ObilinovicCenter for Neural Science, New York University, USA.
Nicolas BrunelDepartment of Neurobiology, Duke University, USA; Department of Physics, Duke University, USA. Electronic address: nicolas.brunel@duke.edu.
Duke University · USNew York University · USUniversity of California San Diego · US

Funding

Canonical computations for motor learning by the cerebellar cortex micro-circuitR01NS112917 · NINDS · DUKE UNIVERSITY · PI LISBERGER, STEPHEN G, MEDINA, JAVIER F · 2019 to 2023
$6.4M
Striatal Plasticity in Habit Formation as a Platform to Deconstruct Adaptive LearningR01NS110059 · NINDS · DUKE UNIVERSITY · PI CALAKOS, NICOLE · 2018 to 2022
$5.2M
Large-scale, neuronal ensemble recordings in motor cortex of the behaving marmosetR01NS104898 · NINDS · UNIVERSITY OF CHICAGO · PI BRUNEL, NICOLAS, HATSOPOULOS, NICHOLAS G · 2018 to 2022
$3.0M
Circuitry underlying response summation in mouse and primate: Theory and experimentU01NS108683 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BRUNEL, NICOLAS, MILLER, KENNETH D · 2018 to 2020
$2.8M
CRCNS: Multiscale dynamics of cortical circuits for visual recognition & memoryR01MH115555 · NIMH · UNIVERSITY OF CHICAGO · PI AMIT, YALI, BRUNEL, NICOLAS · 2017 to 2021
$2.0M
Learning spatio-temporal statistics from the environment in recurrent networksR01EB022891 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BRUNEL, NICOLAS, SHOUVAL, HAREL ZEEV · 2016 to 2018
$1.2M
NIBIB NIH HHS R01 EB022891NIMH NIH HHS R01 MH115555NINDS NIH HHS R01 NS104898NINDS NIH HHS R01 NS110059NINDS NIH HHS R01 NS112917NINDS NIH HHS U01 NS108683
6 · The paper itself

Abstract

The mechanisms of information storage and retrieval in brain circuits are still the subject of debate. It is widely believed that information is stored at least in part through changes in synaptic connectivity in networks that encode this information and that these changes lead in turn to modifications of network dynamics, such that the stored information can be retrieved at a later time. Here, we review recent progress in deriving synaptic plasticity rules from experimental data and in understanding how plasticity rules affect the dynamics of recurrent networks. We show that the dynamics generated by such networks exhibit a large degree of diversity, depending on parameters, similar to experimental observations in vivo during delayed response tasks.

Indexed as

Nerve NetNeural Networks, ComputerInformation Storage and RetrievalModels, NeurologicalNeuronal PlasticitySynapses

Identifiers

PMID34175521
PMCPMC8688181
OpenAlexW3176125083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.