ArticleBMC surgery2021
Risk factors for developing high-output ileostomy in CRC patients: a retrospective study.
Article in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Ghost Ileostomy Versus Loop Ileostomy Following Oncologic Resection for Rectal Cancer: A Systematic Review and Meta-Analysis.Surgical innovation · 2023Pooled it
- Risk factors and prediction model for early high-output stoma after colorectal cancer surgery: A retrospective study.Asia-Pacific journal of oncology nursing · 2026Article
- Comparing the safety and efficacy of virtual ileostomy versus diverting ileostomy in patients undergoing total mesorectal excision for rectal cancer: a propensity-matched study.Surgical endoscopy · 2026Article
- Preoperative Controlling Nutritional Status (CONUT) Score Might Be a Predictive Biomarker of Postoperative Mortality within 90 Days after Surgery in Patients with Malignant Bowel Obstruction Caused by Unresectable Colorectal Cancer.Journal of the anus, rectum and colon · 2026Article
- Gender-specific association between health-related quality of life and sexual function in colorectal cancer patients in Iran: a descriptive-correlational study.International journal of colorectal disease · 2025Article
- Article
- Predictive model for early postoperative stomal complications in colorectal cancer: A systematic review.World journal of gastrointestinal oncology · 2025Article
- Construction and application of home dietary management program for postoperative patients with preventive ileostomy for rectal cancer.Frontiers in nutrition · 2025Article
- Preoperative risk factors for ileostomy-associated kidney injury in colorectal tumor surgery following ileostomy formation.International journal of colorectal disease · 2024Article
- Knowledge, attitudes, practices and associated factors regarding high output stoma of ileostomy among colorectal surgical nurses: a multicentre cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
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10 authors at 1 institution in 1 country.
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Abstract
backgroundAnastomotic leakage is one of the most serious postoperative complications of rectal cancer. Prophylactic ileostomy has been widely used to reduce the risk and severity of complications of anastomotic leakage. However, prophylactic ileostomy itself has some complications, and ileostomy high output syndrome (HOS) is one of them. This study was performed to explore the risk factors of HOS in ileostomy.
methodsA total of 114 patients with HOS were screened out from 494 eligible ileostomy patients in the last 5 years. The relationship between HOS and the clinicopathological data was analyzed using the Chi-square test and Fisher's exact probability. Multivariate analysis was performed by logistic regression.
resultsThe incidence of HOS was 23.07% in this study. Dehydration was the most common symptom of HOS (37.7%). There was no clear correlation between HOS occurrence with sex, age, gross typing, histological grade, tumor location, lymph node metastasis, and TNM stage (p > 0.05). The incidence of HOS was 14/18 in inflammatory bowel disease patients, 18/28 in diabetes mellitus patients, and 23/72 in neoadjuvant chemoradiotherapy patients, 13/17 in total colectomy and abdominal infection patients. Multivariate analysis showed that they are risk factors for HOS (p < 0.05).
conclusionHOS occurred occasionally but rarely studied and lacks attention. Inflammatory bowel disease, diabetes mellitus, neoadjuvant radiotherapy chemotherapy, total colectomy and abdominal infection are the risk factors for HOS.
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