Evidence map›Paper›PMID 34174820›Full record

ArticleBMC immunology2021

Immunization with Pneumocystis carinii A12

Tong Tong, Zhongxin Wang, Yuanhong Xu, Jilu Shen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tong TongDepartment of Clinical Laboratory, First Affiliated Hospital, Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, People's Republic of China.
Zhongxin WangDepartment of Clinical Laboratory, First Affiliated Hospital, Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, People's Republic of China.
Yuanhong XuDepartment of Clinical Laboratory, First Affiliated Hospital, Anhui Medical University, 218 Jixi Road, Hefei, Anhui, 230022, People's Republic of China.
Jilu ShenDepartment of Clinical Laboratory, Fourth Affiliated Hospital, Anhui Medical University, 100 Huaihai Road, Hefei, Anhui, People's Republic of China. shenjilu@126.com.
First Affiliated Hospital of Anhui Medical University · CNAnhui Medical University · CNFourth Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumocystis pneumonia (PcP), which is caused by Pneumocystis carinii, is a life-threatening infection that affects immunocompromised individuals. Unfortunately, chemoprophylaxis and dapsone are only effective for half of the patients with PcP, indicating that additional preventive methods are needed. We predicated the pneumocystis surface protein A12 sequence 1-85 by DNAStar software and BepiPred, and identified it as a potential vaccine candidate by bioresearch.

methodsWe used recombinant A12

resultsOur results showed that immunization with recombinant A12

conclusionsOur findings suggest that A12

Indexed as

AnimalsAntibodies, FungalAntigens, FungalCells, CulturedDisease Models, AnimalFemaleFungal VaccinesHumansImmunizationImmunocompromised HostImmunoglobulin GLungLymphocyte ActivationMiceMice, Inbred BALB CPeptidesA12 antigen, Pneumocystis cariniiAntibodies, FungalAntigens, FungalFungal VaccinesImmunoglobulin GPeptidesRecombinant ProteinsA12ImmunizationInfectionP.cariniiPcP

Identifiers

PMID34174820
PMCPMC8236001
OpenAlexW3174289743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.