Evidence map›Paper›PMID 34174797›Full record

ArticleTurkish journal of medical sciences2021

Allergic bronchopulmonary Aspergillosis in children.

Özge Atay, Suna Asilsoy, Gizem Atakul, Serdar Al, Özge Kangallı Boyacıoğlu, Nevin Uzuner, Özkan Karaman

Open access · bronzeAbstract read
In one paragraph

Article in Turkish journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Non-syndromic hyper-IgE in children: A practical approach.The World Allergy Organization journal · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Özge AtayDepartment of Pediatric Immunology and Allergy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Suna AsilsoyDepartment of Pediatric Immunology and Allergy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Gizem AtakulDepartment of Pediatric Immunology and Allergy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Serdar AlDepartment of Pediatric Immunology and Allergy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Özge Kangallı BoyacıoğluDivision of Nephrology, Department of Internal Medicine, Mersin State Hospital, Mersin, Turkey.
Nevin UzunerDepartment of Pediatric Immunology and Allergy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Özkan KaramanDepartment of Pediatric Immunology and Allergy, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Dokuz Eylül University · TRENT and Allergy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllergic bronchopulmonary aspergillus (ABPA) is a lung disease caused by hypersensitivity from Aspergillus fumigatus. Diagnostic criteria, staging systems and treatment methods for ABPA disease have been reported in studies evaluating populations, the majority of which are adult patients. Our study aimed to discuss the use of ABPA diagnostic criteria in children, the success of other alternative regimens to oral corticosteroids in the treatment of ABPA, and the changes that occur during treatment, in the light of the literature.

methodsBetween January 2017 and 2020, patients diagnosed with ABPA at the Dokuz Eylül University Child Allergy and Immunology clinic were identified; demographic characteristics, clinical and laboratory findings, diagnostic scores and stages, and treatment protocols were analyzed retrospectively.

resultsThe mean age of patients diagnosed with ABPA was 14.33 ± 1.96. At the time of ABPA diagnosis, the median total IgE level was 1033 IU/mL (1004-6129), and the median AF specific IgE was 10.64 (2.59-49.70) kU/L. Bronchiectasis was detected in HRCT of 5 cases. We detected significant improvement in spirometric analysis with omalizumab treatment in our patient with steroid-related complications. DISCUSSION: Today, although risk factors have been investigated for ABPA, it has not been revealed clearly. Both diagnostic criteria and treatment regimens have been described in research studies, mostly adults. In pediatric patients; clarification of diagnosis and treatment algorithms is necessary to prevent irreversible lung tissue damage and possible drug side effects.

Indexed as

Aspergillosis, Allergic BronchopulmonaryBronchiectasisAdultChildHumansImmunoglobulin ERetrospective StudiesSpirometryImmunoglobulin EAllergic bronchopulmonary aspergillosisasthmachildcystic fibrosis

Identifiers

PMID34174797
PMCPMC8742489
OpenAlexW3175235066

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.