Evidence map›Paper›PMID 34174494›Full record

ArticleThe journal of allergy and clinical immunology. In practice2021

Detection of Food Allergens in School and Home Environments of Elementary Students.

Michelle C Maciag, William J Sheehan, Lisa M Bartnikas, Peggy S Lai, Carter R Petty, Stephanie Filep, Martin D Chapman, Wanda Phipatanakul

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. The Role of the Indoor Exposome in Food Allergy Development.Current allergy and asthma reports · 2026
    Review
  2. A novel ambient air sampler for detection of allergens and endotoxin.The journal of allergy and clinical immunology. Global · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Food Allergies in Inner-City Schools: Addressing Disparities and Improving Management.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Michelle C MaciagDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass; Asthma & Allergy Affiliates, Salem, Mass.
William J SheehanDivision of Allergy and Immunology, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC.
Lisa M BartnikasDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
Peggy S LaiDepartment of Pediatrics, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, Mass.
Carter R PettyBiostatistics and Research Design Core, Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Mass.
Stephanie FilepIndoor Biotechnologies, Charlottesville, Va.
Martin D ChapmanIndoor Biotechnologies, Charlottesville, Va.
Wanda PhipatanakulDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Wanda.Phipatanakul@childrens.harvard.edu.
Boston Children's Hospital · USIndoor Biotechnologies (United States) · USGeorge Washington University · USHarvard University · USMassachusetts General Hospital · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Controlling and preventing Asthma progression and Severity in Kids (CASK)U01AI126614 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2016 to 2023
$21.0M
MOLECULAR BASIS OF ALLERGIC AND IMMUNOLOGIC DISEASET32AI007512 · NIAID · CHILDREN'S HOSPITAL BOSTON · PI Janet Chou, Peter A Nigrovic · 1996 to 2026
$13.1M
SICAS- Diversity SupplementU01AI110397 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2015 to 2020
$8.8M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
ALLERGENS IN INNER-CITY SCHOOLS AND CHILDHOOD ASTHMAR01AI073964 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2008 to 2012
$4.6M
The school microbiome and asthma morbidity in inner-city childrenR01AI144119 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAI, PEGGY SUE · 2019 to 2023
$3.7M
Environmental Risk Factors for Pediatric Sleep Disordered BreathingR01HL137192 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2017 to 2020
$3.5M
Novel NOTCH4 Pathway of Asthma Severity in Urban School Children: Clinical Research Center, Boston Children’s HospitalU01AI160087 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI Talal Amine Chatila, WANDA PHIPATANAKUL · 2021 to 2026
$2.8M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
Evaluating the Impact of School Nut-Free PoliciesK23AI143962 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI BARTNIKAS, LISA MARIE · 2019 to 2023
$970k
Role of Peanut Allergen in Urban Schools and PreschoolsK23AI104780 · NIAID · CHILDREN'S RESEARCH INSTITUTE · PI SHEEHAN, WILLIAM JAMES · 2014 to 2018
$912k
NCATS NIH HHS UL1 TR001102NHLBI NIH HHS R01 HL137192NHLBI NIH HHS U10 HL098102NIAID NIH HHS K23 AI104780NIAID NIH HHS K23 AI143962NIAID NIH HHS K24 AI106822NIAID NIH HHS R01 AI073964NIAID NIH HHS R01 AI144119NIAID NIH HHS T32 AI007512NIAID NIH HHS U01 AI110397NIAID NIH HHS U01 AI126614NIAID NIH HHS U01 AI160087
6 · The paper itself

Abstract

backgroundLittle is known about environmental food allergen exposure on school surfaces.

objectiveTo compare the distribution of major food allergens in floor dust and table wipe samples from elementary schools and dust samples from students' homes.

methodsIn this substudy of the School Inner-City Asthma Study-II, 103 table wipe samples and 98 floor dust samples from cafeterias and classrooms in 18 elementary schools were analyzed for milk, peanut, cashew, hazelnut, and egg using a multiplex array. Home kitchen floor and bed dust samples from 90 students were also analyzed.

resultsFood allergens were detectable in schools, but at significantly lower levels than in homes (P < .001). In schools, milk and peanut were detected in all table wipe samples; milk and egg were detected in all floor dust samples. Cafeteria table wipe samples contained significantly higher levels of milk, peanut, hazelnut, and egg, compared with classrooms. Cafeteria floor dust samples contained higher levels milk than classrooms. Peanut-restrictive policies did not consistently reduce environmental peanut exposure in schools. Peanut allergen was lower in dust from homes of students with peanut allergy (n = 5) compared with those without peanut allergy (n = 85) (P < .001). Reassuringly, peanut allergen in the schools of peanut-allergic students was not significantly different than in their homes.

conclusionFood allergens were readily detectable on tables and floors in elementary schools, but at levels lower than in students' homes. For peanut-allergic students, the levels of detectable peanut in their schools were not higher than their homes. The low levels of detectable food allergens in school environments are unlikely to result in severe allergic reactions.

Indexed as

Food HypersensitivitySchoolsAllergensChildDustHumansStudentsAllergensDustEnvironmentExposureFood allergenFood allergyInner-cityMultiplex array for foodsSchool

Identifiers

PMID34174494
PMCPMC8511097
OpenAlexW3175376166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.