Evidence map›Paper›PMID 34174212›Full record

Trial reportJornal de pediatria

Randomized trial with soaps - what happens to a newborn baby's skin?

Larissa Habib Mendonça Gois Topan, Vânia Oliveira Carvalho, Kerstin Taniguchi Abagge

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Children's soap pH analysis and its meaning in children's skin cleansing.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Larissa Habib Mendonça Gois TopanUniversidade Federal do Paraná, Departamento de Pediatria, Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Curitiba, PR, Brazil. Electronic address: larissa.gois@ebserh.gov.br.
Vânia Oliveira CarvalhoUniversidade Federal do Paraná, Departamento de Pediatria, Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Curitiba, PR, Brazil.
Kerstin Taniguchi AbaggeUniversidade Federal do Paraná, Departamento de Pediatria, Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Curitiba, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate the effectiveness of a children's soap with physiological pH in maintaining cutaneous pH and moisture of the newborn (NB)'s skin after the first bath.

methodsRandomized, controlled and double-blind clinical trial in a rooming-in of a tertiary maternity hospital in southern Brazil with 204 newborns > 34 gestational weeks. Gestational and obstetric history was evaluated, and newborns were randomized into two groups according to the product applied in the bath: the control group (CG), which used common liquid soap with pH 7.0 and experimental group (EG), which used children's liquid soap with pH 5.8. Evaluation was made immediately before and after bath with skin pH measurement, corneometry and clinical parameters (erythema, scaling and moisture), on the forehead, abdomen and thigh.

resultsThere was no difference between groups regarding gestational, obstetric and family history (p > 0.05). In CG, skin pH increased in the abdomen and thigh (p < 0.05). In EG there was an improvement in clinical parameters after bathing with: increased moisture, less erythema and less scaling (p < 0.05). On the forehead, there was a significant increase in pH after bathing (p < 0.001) similar in both groups, although no use of soap. There was no difference in corneometry between groups after bathing.

conclusionChildren's liquid soap with physiological pH maintained the acidic skin pH and moisture of the newborn's skin after the first bath, which reinforces the importance of using products with physiological pH in the hygiene of newborns. Registration number RBR-9ky84vd.

Indexed as

BathsSoapsBrazilChildErythemaFemaleHumansInfantInfant, NewbornPregnancySoapsAcidificationBath and immersion productsNewbornPersonal hygiene productsSkin hygiene

Identifiers

PMID34174212
PMCPMC9432187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.