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ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2021

Epidemiology and outcomes of open globe injuries: the international globe and adnexal trauma epidemiology study (IGATES).

Annette K Hoskin, Rebecca Low, Parveen Sen, Chitaranjan Mishra, Tengku Ain Kamalden, Fasika Woreta, Mehul Shah, Marian Pauly, Andres Rousselot, Gangadhara Sundar and 6 more

Erratum issuedAbstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
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  6. Observational
  7. Significant increase of firework induced eye injuries in Germany and The Netherlands- are we doing enough to protect minors and bystanders?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  8. Article
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  10. Review
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  12. Association of open globe injury characteristics with outcome measures in the emergency department.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  13. Article
  14. Article
  15. The application of clinical registries in ophthalmic trauma-the International Globe and Adnexal Trauma Epidemiology Study (IGATES).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Review
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  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Annette K HoskinSave Sight Institute, Discipline of Ophthalmology, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Rebecca LowDepartment of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Novena, 308433, Singapore.
Parveen SenSankara Nethralaya, Chennai, India.
Chitaranjan MishraAravind Eye Hospital, Madurai, India.
Tengku Ain KamaldenUM Eye Research Centre, University of Malaya, Kuala Lumpur, Malaysia.
Fasika WoretaWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mehul ShahDrashti Nethralaya Eye Hospital, Dahod, India.
Marian PaulyGiridhar Eye Institute, Kochi, Kerala, India.
Andres RousselotConsultorios Oftalmológicos Benisek Ascarza, Capital Federal, Buenos Aires, Argentina.
Gangadhara SundarNational University Hospital, Kent Ridge, Singapore.
Sundaram NatarajanAditya Jyot Eye Hospital, Mumbai, India.
Lisa KeaySchool of Optometry and Vision Science, UNSW, Sydney, Australia.
Dinesh Visva GunasekeranSchool of Medicine, National University of Singapore, Kent Ridge, Singapore.
Stephanie L WatsonSave Sight Institute, Discipline of Ophthalmology, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Rupesh AgrawalDepartment of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Novena, 308433, Singapore. Rupesh_agrawal@ttsh.com.sg.ORCID http://orcid.org/0000-0002-6662-5850
IGATES Study Group - An Asia Pacific Ophthalmic Trauma Society publication

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo detail the methodology for a novel ocular trauma registry and utilize the registry to determine the demographics, nature of injury, and associations of severe visual loss for open globe injuries (OGI).

methodsThirteen hospitals in 7 countries used International Globe and Adnexal Trauma Epidemiology Study (IGATES) platform. Patients presenting between April 2009 and 2020 with OGI (with or without) adnexal involvement or intraocular foreign body (IOFB) were included.

resultsAnalyses of presenting and final VA, using "severe vision loss" (VA ≤ 6/60) and "no severe loss" (VA > 6/60), were performed. Four hundred fifty-four (64%) patients had VA < 6/60 at presentation and 327 (44.8%) at final follow-up, with a highly significant association between presenting and final VA (p < 0.0001). From the cohort of 746 patients, 37 were missing VA at presentation and 16 at follow-up and complete clinical data was available for 354 patients. The male to female ratio is 6:1, and mean age 36.0 ± 20.0 years old. Relative afferent pupillary defect (RAPD), zone III injury, IOFB, and eyelid injury at presentation were recorded in 50 (6.7%), 55 (7.8%), 97 (13%), and 87 (11.7%) patients, respectively, and were significantly associated with VA < 6/60 at follow-up. Older age, ≥ 61 years, was associated with 3.39 times (95% CI: 1.95-5.89) higher risk than ≤20-year-old patients (p < 0.0001) and males 0.424 times (95% CI: 0.27-0.70) lower risk than female (p = 0.0001) of severe vision loss (SVL).

conclusionIn OGIs from 13 hospitals, female gender, older age, zone III injury, eyelid injury, and IOFB were associated with higher risk of visual outcome of SVL.

Indexed as

Eye Foreign BodiesEye Injuries, PenetratingAdolescentAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesVision DisordersVisual AcuityYoung AdultOcular traumaOpen globe injuryPreventionRegistryVision loss

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.