Evidence map›Paper›PMID 34173846›Full record

ArticleApplied microbiology and biotechnology2021

A strategic approach to apply bacterial substances for increasing metabolite productions of Euglena gracilis in the bioreactor.

Da Hee Kim, Jee Young Kim, Jeong-Joo Oh, Min Seo Jeon, Hye Suck An, Cho Rok Jin, Yoon-E Choi

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Mixotrophic Cultivation of a Native Cyanobacterium,Journal of microbiology and biotechnology · 2022
    Article
  2. Life (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Da Hee KimDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea.
Jee Young KimDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea.
Jeong-Joo OhDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea.
Min Seo JeonDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea.
Hye Suck AnMarine Biology Research Division, National Marine Biodiversity Institute of Korea, Chungcheongnam-do, Seocheon, 33662, Republic of Korea.
Cho Rok JinDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea.
Yoon-E ChoiDivision of Environmental Science & Ecological Engineering, Korea University, Seoul, 02841, Republic of Korea. yechoi@korea.ac.kr.ORCID http://orcid.org/0000-0002-3106-1610
Korea University · KRMarine Biodiversity Institute of Korea · KR

Funding

Korea Institute of Marine Science and Technology 20170488National Research Foundation of Korea NRF-2019R1A2C2087449
6 · The paper itself

Abstract

Bacterial extracellular polymeric substances (EPS) are promising materials that have a role in enhancing growth, metabolite production, and harvesting efficiency. However, the validity of the EPS effectiveness in scale-up cultivation of microalgae is still unknown. Therefore, in order to verify whether the bacterial metabolites work in the scale-up fermentation of microalgae, we conducted a bioreactor fermentation following the addition of bacterial EPS derived from the marine bacterium, Pseudoalteromonas sp., to Euglena gracilis. Various culture strategies (i.e., batch, glucose fed-batch, and glucose and EPS fed-batch) were conducted to maximize metabolite production of E. gracilis in scale-up cultivation. Consequently, biomass and paramylon concentrations in the continuous glucose and EPS-treated culture were enhanced by 3.0-fold and 4.2-fold (36.1 ± 1.4 g L

Indexed as

Euglena gracilisMicroalgaeBiomassBioreactorsFermentationEuglena gracilisExtracellular polymeric substancesFed-batch fermentationHarvestingParamylon

Identifiers

PMID34173846
OpenAlexW3173994494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.