Evidence map›Paper›PMID 34173663›Full record

ReviewJournal of the Pediatric Infectious Diseases Society2021

Sinus Bradycardia in a Pediatric Patient Treated With Remdesivir for Acute Coronavirus Disease 2019: A Case Report and a Review of the Literature.

Eric J Chow, Branden Maust, Katherine M Kazmier, Caleb Stokes

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Journal of the Pediatric Infectious Diseases Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Remdesivir: treatment of COVID-19 in special populations.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  5. Article
  6. Article
  7. Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children.Infectious disease clinics of North America · 2022
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Eric J ChowDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-3349-9330
Branden MaustDepartment of Pediatrics, Division of Infectious Diseases, Seattle Children's Hospital and University of Washington, Seattle, Washington, USA.
Katherine M KazmierDepartment of Pediatrics, Division of Hospital Medicine, Seattle Children's Hospital and University of Washington, Seattle, Washington, USA.
Caleb StokesDepartment of Pediatrics, Division of Infectious Diseases, Seattle Children's Hospital and University of Washington, Seattle, Washington, USA.
Seattle Children's Hospital · USUniversity of Washington · US

Funding

HOST DEFENSE TRAINING IN ALLERGY AND INFECTIOUS DISEASEST32AI007044 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID Neal FREDRICKS · 1985 to 2026
$14.6M
ACADEMIC PEDIATRIC INFECTIOUS DISEASET32HD007233 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI KEVIN B URDAHL · 1985 to 2026
$6.7M
Innate Immunity of Zika Virus Infection In Human Neural ProgenitorsK08AI150996 · NIAID · UNIVERSITY OF WASHINGTON · PI STOKES, CALEB · 2020 to 2024
$975k
National Institute of Allergy and Infectious Diseases K08AI150996-01NIAID NIH HHS K08 AI150996NIAID NIH HHS T32 AI007044NICHD NIH HHS T32 HD007233
6 · The paper itself

Abstract

Remdesivir is an RNA polymerase inhibitor that is commonly used in the treatment of patients with severe acute coronavirus disease 2019 (COVID-19). As the severe acute respiratory syndrome coronavirus 2 spreads, the use of remdesivir is likely to increase. Most of the patients treated with remdesivir will not experience any adverse events although some side effects have been reported. Here, we describe a case of sinus bradycardia associated with remdesivir therapy in a pediatric patient with severe acute COVID-19.

Indexed as

COVID-19 Drug TreatmentAdenosine MonophosphateAlanineAntiviral AgentsBradycardiaChildHumansSARS-CoV-2Adenosine MonophosphateAlanineAntiviral AgentsremdesivirbradycardiaCOVID-19pediatricsremdesivirSARS-CoV-2

Identifiers

PMID34173663
PMCPMC8557381
OpenAlexW3174041905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.