Evidence map›Paper›PMID 34173273›Full record

ArticleJournal of cardiac surgery2021

A multicentre roadmap to restart elective cardiac surgery after COVID-19 peak in an Italian epicenter.

Fabrizio Rosati, Claudio Muneretto, Massimo Baudo, Giuseppe D'Ancona, Samuele Bichi, Maurizio Merlo, Besart Cuko, Piersilvio Gerometta, Valentina Grazioli, Laura Giroletti and 3 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of cardiac surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. From COVID-19 or because COVID-19?Journal of cardiac surgery · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Fabrizio RosatiDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0002-1475-3156
Claudio MunerettoDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Massimo BaudoDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0003-3754-6704
Giuseppe D'AnconaDepartment of Cardiovascular Research, Vivantes Klinikum Urban, Berlin, Germany.
Samuele BichiDivision of Cardiac Surgery, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Maurizio MerloDivision of Cardiac Surgery, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Besart CukoDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.ORCID http://orcid.org/0000-0001-6207-7124
Piersilvio GeromettaDivision of Cardiac Surgery, Humanitas Gavazzeni, Bergamo, Italy.
Valentina GrazioliDivision of Cardiac Surgery, Humanitas Gavazzeni, Bergamo, Italy.ORCID http://orcid.org/0000-0002-3251-7659
Laura GirolettiDivision of Cardiac Surgery, Humanitas Gavazzeni, Bergamo, Italy.
Lorenzo Di BaccoDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Alberto RepossiniDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Stefano BenussiDivision of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITHumanitas Gavazzeni · ITOspedale Papa Giovanni XXIII · ITVivantes Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the Italian Phase-2 of the coronavirus pandemic, it was possible to restart elective surgeries. Because hospitals were still burdened with coronavirus disease 2019 (COVID-19) patients, it was focal to design a separate "clean path" for the surgical candidates and determine the possible effects of major surgery on previously infected patients.

methodsFrom May to July 2020 (postpandemic peak), 259 consecutive patients were scheduled for elective cardiac surgery in three different centers. Our original roadmap with four screening steps included: a short item questionnaire (STEP-1), nasopharyngeal swab (NP) (STEP-2), computed tomography (CT)-scan using COVID-19 reporting and data system (CO-RADS) scoring (STEP-3), and final NP swab before discharge (STEP-4).

resultsTwo patients (0.8%) resulted positive at STEP-2: one patient was discharged home for quarantine, the other performed a CT-scan (CO-RADS: <2), and underwent surgery for unstable angina. Chest-CT was positive in 6.3% (15/237) with mean CO-RADS of 2.93 ± 0.8. Mild-moderate lung inflammation (CO-RADS: 2-4) did not delay surgery. Perioperative mortality was 1.15% (3/259), and cumulative incidence of pulmonary complications was 14.6%. At multivariable analysis, only age and cardiopulmonary bypass (CPB) time were independently related to pulmonary complications composite outcome (age >75 years: odds ratio [OR]: 2.6; 95% confidence interval [CI]: 1.25-5.57; p = 0.011; CPB >90 min. OR: 4.3; 95% CI: 1.84-10.16; p = 0.001). At 30 days, no periprocedural contagion and rehospitalization for COVID-19 infections were reported.

conclusionsOur structured roadmap supports the safe restarting of an elective cardiac surgery list after a peak of a still ongoing COVID-19 pandemic in an epicenter area. Mild to moderate CT residuals of coronavirus pneumonia do not justify elective cardiac surgery procrastination.

Indexed as

Cardiac Surgical ProceduresCOVID-19AgedHumansItalyPandemicsSARS-CoV-2cardiac surgerycoronavirus disease 2019public health

Identifiers

PMID34173273
PMCPMC9292840
OpenAlexW3176021535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.