Evidence map›Paper›PMID 34173112›Full record

ArticleBulletin of experimental biology and medicine2021

Response of Pituitary-Thyroid Axis to a Short-Term Shift in Deuterium Content in the Body.

N V Yaglova, S S Obernikhin, E P Timokhina, V V Yaglov

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. The Best Material from the VII Congress of Russian Biophysicists.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Emerging Role of Deuterium/Protium Disbalance in Cell Cycle and Apoptosis.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Impact of Reduced Deuterium Intake on Thermoregulation.Bulletin of experimental biology and medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

N V YaglovaResearch Institute of Human Morphology, Moscow, Russia. yaglova@mail.ru.
S S ObernikhinResearch Institute of Human Morphology, Moscow, Russia.
E P TimokhinaResearch Institute of Human Morphology, Moscow, Russia.
V V YaglovResearch Institute of Human Morphology, Moscow, Russia.
Research Institute of Human Morphology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied functional changes in rat pituitary-thyroid axis after a short-term shift in deuterium body content. Male Wistar rats consumed deuterium-enriched (500,000 ppm) or deuterium-depleted water (10 ppm) for 24 h. Rats of both experimental groups demonstrated elevated concentration of bound with transport proteins thyroxine and reduced level of thyroid-stimulating hormone in serum. No changes in the rate of thyroxine conversion to triiodothyronine were found. Thus, both the increase and reduction of deuterium body content produced similar changes in the function of the pituitary-thyroid axis with primary affection of the thyroid gland, indicative of its higher sensitivity to shift in deuterium levels.

Indexed as

AnimalsBody FluidsBody WeightDeuteriumFluid ShiftsMaleOrgan SizePituitary GlandRatsRats, WistarThyroid GlandThyrotropinThyroxineTriiodothyronineWater-Electrolyte BalanceDeuteriumThyrotropinThyroxineTriiodothyroninedeuteriumpituitary glandprotiumthyroidthyroid hormones

Identifiers

PMID34173112
OpenAlexW3174684953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.