Evidence map›Paper›PMID 34173105›Full record

ArticleBulletin of experimental biology and medicine2021

Spike Activity in the Ventromedial Nucleus of Rat Hypothalamus during Aging.

K Yu Moiseev, A A Spirichev, L G Pankrasheva, A S Martyusheva, A Yu Abramova, P M Maslyukov

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

K Yu MoiseevYaroslalv State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russia.
A A SpirichevYaroslalv State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russia.
L G PankrashevaYaroslalv State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russia.
A S MartyushevaP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
A Yu AbramovaP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
P M MaslyukovYaroslalv State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russia. mpm@ysmu.ru.
Institute of Normal Physiology named after P.K. Anokhin · RUMinistry of Health of the Russian Federation · RUYaroslavl State Medical Academy · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spike activity of neurons in the ventromedial nucleus (VMN) of the hypothalamus in adult (6-8 months) and aged (2 years) male rats was studied by the in vivo extracellular method using stereotaxic insertion of microelectrodes. In all animals, firing frequency of most VMN neurons increased in response to glucose administration. However, in aged rats, the mean baseline and glucose-induced spike frequencies of VMN neurons were lower than in adult animals. These results support the hypothesis that aging is associated with a decrease in the functional activity of hypothalamic neurons.

Indexed as

Action PotentialsAgingAnimalsCortical ExcitabilityElectrophysiological PhenomenaGlucoseHypothalamusInsulinMaleNeuronsRatsRats, WistarVentromedial Hypothalamic NucleusGlucoseInsulinaginghypothalamusspike frequencyventromedial nucleus

Identifiers

PMID34173105
OpenAlexW3175270639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.