Evidence map›Paper›PMID 34173102›Full record

ArticleBulletin of experimental biology and medicine2021

Pulmonary Microcirculation during Experimental Pulmonary Thromboembolism under Conditions of Activation and Blockade of Muscarinic Acetylcholine Receptors.

V I Evlakhov, T P Berezina, I Z Poyassov, V I Ovsyannikov

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

V I EvlakhovLaboratory of Physiology of the Visceral System, Institute of the Experimental Medicine, St. Petersburg, Russia. viespbru@mail.ru.
T P BerezinaLaboratory of Physiology of the Visceral System, Institute of the Experimental Medicine, St. Petersburg, Russia.
I Z PoyassovLaboratory of Physiology of the Visceral System, Institute of the Experimental Medicine, St. Petersburg, Russia.
V I OvsyannikovLaboratory of Physiology of the Visceral System, Institute of the Experimental Medicine, St. Petersburg, Russia.
Institute of Experimental Medicine · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in pulmonary microcirculation were studied in isolated perfused rabbit lungs during modelling pulmonary thromboembolism under conditions of acetylcholine infusion against the background of treatment with M1 acetylcholine receptor blocker pirenzepine or blockade of muscarinic acetylcholine receptors with atropine. In the first case, the increase in pulmonary artery pressure was less pronounced than in case of atropine treatment. In response to pulmonary embolism after acetylcholine infusion against the background of pirenzepine pretreatment, the capillary hydrostatic pressure and postcapillary resistance did not change, while after atropine treatment, these parameters increased. In case of pulmonary embolism after acetylcholine infusion combined with selective blockade of M1 muscarinic acetylcholine receptors, the capillary filtration coefficient increased to a greater extent, than in the control and after blockade of muscarinic acetylcholine receptors.

Indexed as

Pulmonary EmbolismAcetylcholineAnimalsAtropineBlood PressureDisease Models, AnimalLungMicrocirculationMuscarinic AntagonistsNitroglycerinPulmonary CirculationRabbitsReceptors, MuscarinicVascular ResistanceAcetylcholineAtropineMuscarinic AntagonistsNitroglycerinReceptors, Muscarinicatropinecapillary filtration coefficientmuscarinic acetylcholine receptorspirenzepinepulmonary thromboembolism

Identifiers

PMID34173102
OpenAlexW3174571660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.