ArticleNature communications2021
Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Molecular Mechanism of the Catalytic Radical Termination in Fatty Acid Photodecarboxylase.Journal of the American Chemical Society · 2026Article
- Stereoselective hydrogen isotope exchange on nicotinamide cofactors through flavoenzyme microscopic reversibility.Chemical science · 2026Article
- Establishing the Fatty Acid PhotodecarboxylaseACS catalysis · 2026Article
- Electricity-driven site-selective deuteration of pharmaceuticals.Chemical science · 2026Article
- Designing and Engineering Enzymes for New-to-Nature Photobiocatalysis.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Enantioselective Radical Hydrocyanoalkylation of Alkenes via Photoenzymatic Catalysis.JACS Au · 2025Article
- Transitioning enzyme catalysis towards photocatalysis.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025Review
- Exploring the Increased Activity of the Blue Light-Dependent Photoenzyme Fatty Acid Photodecarboxylase under Violet Light.ACS catalysis · 2025Article
- Cavity-Based Discovery of New Fatty Acid Photodecarboxylases.Chembiochem : a European journal of chemical biology · 2024Article
- Stereodivergent photobiocatalytic radical cyclization through the repurposing and directed evolution of fatty acid photodecarboxylases.Nature chemistry · 2024Article
- Review
- Photobiocatalytic Strategies for Organic Synthesis.Chemical reviews · 2023Review
- Autocatalytic effect boosts the production of medium-chain hydrocarbons by fatty acid photodecarboxylase.Science advances · 2023Article
- Ultrafast Dynamics of Fatty Acid Photodecarboxylase in Anionic Semiquinone State.The journal of physical chemistry letters · 2022Article
- Strategies for Transferring Photobiocatalysis to Continuous Flow Exemplified by Photodecarboxylation of Fatty Acids.ACS catalysis · 2022Article
- Making Enzymes Suitable for Organic Chemistry by Rational Protein Design.Chembiochem : a European journal of chemical biology · 2022Review
- Site-Specific and Degree-Controlled Alkyl Deuteration via Cu-Catalyzed Redox-Neutral Deacylation.Journal of the American Chemical Society · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the well-established chemical processes for C-D bond formation, the toolbox of enzymatic methodologies for deuterium incorporation has remained underdeveloped. Here we describe a photodecarboxylase from Chlorella variabilis NC64A (CvFAP)-catalyzed approach for the decarboxylative deuteration of various carboxylic acids by employing D
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