Evidence map›Paper›PMID 34172744›Full record

ArticleNature communications2021

Polymer cyclization for the emergence of hierarchical nanostructures.

Chaojian Chen, Manjesh Kumar Singh, Katrin Wunderlich, Sean Harvey, Colette J Whitfield, Zhixuan Zhou, Manfred Wagner, Katharina Landfester, Ingo Lieberwirth, George Fytas and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Diagnostic potential of blood plasma longitudinal viscosity measured using Brillouin light scattering.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chaojian ChenMax Planck Institute for Polymer Research, Mainz, Germany.ORCID 0000-0002-2588-2447
Manjesh Kumar SinghDepartment of Mechanical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.ORCID 0000-0002-9156-3495
Katrin WunderlichMax Planck Institute for Polymer Research, Mainz, Germany.
Sean HarveyMax Planck Institute for Polymer Research, Mainz, Germany.
Colette J WhitfieldMax Planck Institute for Polymer Research, Mainz, Germany.ORCID 0000-0003-2288-0128
Zhixuan ZhouMax Planck Institute for Polymer Research, Mainz, Germany.
Manfred WagnerMax Planck Institute for Polymer Research, Mainz, Germany.
Katharina LandfesterMax Planck Institute for Polymer Research, Mainz, Germany.
Ingo LieberwirthMax Planck Institute for Polymer Research, Mainz, Germany.
George FytasMax Planck Institute for Polymer Research, Mainz, Germany.
Kurt KremerMax Planck Institute for Polymer Research, Mainz, Germany.ORCID 0000-0003-1842-9369
Debashish MukherjiQuantum Matter Institute, University of British Columbia, Vancouver, Canada.
David Y W NgMax Planck Institute for Polymer Research, Mainz, Germany. david.ng@mpip-mainz.mpg.de.ORCID 0000-0002-0302-0678
Tanja WeilMax Planck Institute for Polymer Research, Mainz, Germany. weil@mpip-mainz.mpg.de.ORCID 0000-0002-5906-7205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The creation of synthetic polymer nanoobjects with well-defined hierarchical structures is important for a wide range of applications such as nanomaterial synthesis, catalysis, and therapeutics. Inspired by the programmability and precise three-dimensional architectures of biomolecules, here we demonstrate the strategy of fabricating controlled hierarchical structures through self-assembly of folded synthetic polymers. Linear poly(2-hydroxyethyl methacrylate) of different lengths are folded into cyclic polymers and their self-assembly into hierarchical structures is elucidated by various experimental techniques and molecular dynamics simulations. Based on their structural similarity, macrocyclic brush polymers with amphiphilic block side chains are synthesized, which can self-assemble into wormlike and higher-ordered structures. Our work points out the vital role of polymer folding in macromolecular self-assembly and establishes a versatile approach for constructing biomimetic hierarchical assemblies.

Identifiers

PMID34172744
PMCPMC8233313

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.