ArticleProceedings of the National Academy of Sciences of the United States of America2021
Ion-dependent protein-surface interactions from intrinsic solvent response.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Molecular Surface Chemistry Drives Anomalous Clustering of Ultrasmall Silica Nanoparticles.The journal of physical chemistry letters · 2026Article
- Impact of solvent forces and broken symmetry on the assembly of designed proteins at a liquid-solid interface.Nature communications · 2026Article
- Elucidating the Supramolecular Interaction of Positively Supercharged Fluorescent Protein with Anionic Phthalocyanines.Advanced biology · 2025Article
- Article
- Self-consistent determination of long-range electrostatics in neural network potentials.Nature communications · 2022Article
- A deterministic code for transcription factor-DNA recognition through computation of binding interfaces.NAR genomics and bioinformatics · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phyllosilicate mineral muscovite mica is widely used as a surface template for the patterning of macromolecules, yet a molecular understanding of its surface chemistry under varying solution conditions, required to predict and control the self-assembly of adsorbed species, is lacking. We utilize all-atom molecular dynamics simulations in conjunction with an electrostatic analysis based in local molecular field theory that affords a clean separation of long-range and short-range electrostatics. Using water polarization response as a measure of the electric fields that arise from patterned, surface-bound ions that direct the adsorption of charged macromolecules, we apply a Landau theory of forces induced by asymmetrically polarized surfaces to compute protein-surface interactions for two muscovite-binding proteins (DHR10-mica6 and
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