Evidence map›Paper›PMID 34172578›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Prem Swaroop Yadav, Shuhao Feng, Qian Cong, Hanjun Kim, Yuchen Liu, Yingzi Yang

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Deletion of aJOR spine · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Loss of Stat3 in Prx1Advanced biology · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Loss of Stat3 in OsterixCell & bioscience · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prem Swaroop YadavDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.ORCID 0000-0003-2213-5320
Shuhao FengDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
Qian CongDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
Hanjun KimDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.ORCID 0000-0001-9364-462X
Yuchen LiuDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115.
Yingzi YangDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115; yingzi_yang@hsdm.harvard.edu.ORCID 0000-0003-3933-887X
Harvard University · US

Funding

Gas-Hedgehog signaling in intramembranous bone formation and expansionR01DE025866 · NIDCR · HARVARD MEDICAL SCHOOL · PI Yingzi Yang · 2016 to 2026
$5.3M
Molecular Mechanism of Wnt/Planar Cell Polarity SignalingR01AR070877 · NIAMS · HARVARD MEDICAL SCHOOL · PI YANG, YINGZI · 2017 to 2022
$3.0M
Cellular and molecular mechanism of Hippo signaling in suppressing liver tumor formationR01CA222571 · NCI · HARVARD MEDICAL SCHOOL · PI YANG, YINGZI · 2018 to 2022
$1.9M
NCI NIH HHS R01 CA222571NIAMS NIH HHS R01 AR070877NIDCR NIH HHS R01 DE025866
6 · The paper itself

Abstract

Job syndrome is a rare genetic disorder caused by

Indexed as

Wnt Signaling PathwayAllelesAnimalsBone and BonesCartilageCell DifferentiationEmbryo, MammalianExtremitiesGene DeletionHumansIntegrasesJob SyndromeLow Density Lipoprotein Receptor-Related Protein-5Mesenchymal Stem CellsMesodermMice, TransgenicCre recombinaseIntegrasesLow Density Lipoprotein Receptor-Related Protein-5Lrp5 protein, mouseSTAT3 Transcription Factorbone developmentJob syndromeSostStat3Wnt/beta-catenin signaling

Identifiers

PMID34172578
PMCPMC8256036
OpenAlexW3173248992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.