Evidence map›Paper›PMID 34172454›Full record

ArticleScience advances2021

Opto-refrigerative tweezers.

Jingang Li, Zhihan Chen, Yaoran Liu, Pavana Siddhartha Kollipara, Yichao Feng, Zhenglong Zhang, Yuebing Zheng

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Ice-phase optothermal tweezers.Nature communications · 2026
    Article
  2. Article
  3. Isolation Techniques of Micro/Nano-Scaled Species for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  4. Perspective: Thermophoresis and Its Promise for Optical Patterning.Langmuir : the ACS journal of surfaces and colloids · 2025
    Review
  5. Photopyroelectric tweezers for versatile manipulation.Innovation (Cambridge (Mass.)) · 2025
    Article
  6. Review
  7. Thermo-optical tweezers based on photothermal waveguides.Microsystems & nanoengineering · 2024
    Article
  8. Optothermal Needle-Free Injection of Vaterite Nanocapsules.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. Hypothermal opto-thermophoretic tweezers.Nature communications · 2023
    Article
  11. Nucleation and Growth of Bipyramidal Yb:LiYFChemistry of materials : a publication of the American Chemical Society · 2023
    Article
  12. Article
  13. Review
  14. Optothermal rotation of micro-/nano-objects.Chemical communications (Cambridge, England) · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Heat-Mediated Optical Manipulation.Chemical reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingang LiMaterials Science and Engineering Program and Texas Materials Institute, The University of Texas at Austin, Austin, TX 78712, USA.ORCID http://orcid.org/0000-0003-0827-9758
Zhihan ChenMaterials Science and Engineering Program and Texas Materials Institute, The University of Texas at Austin, Austin, TX 78712, USA.
Yaoran LiuDepartment of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX 78705, USA.
Pavana Siddhartha KolliparaWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX 78712, USA.ORCID http://orcid.org/0000-0003-0166-6720
Yichao FengSchool of Physics and Information Technology, Shaanxi Normal University, Xi'an, Shaanxi 710062, China.ORCID http://orcid.org/0000-0002-3587-3827
Zhenglong ZhangSchool of Physics and Information Technology, Shaanxi Normal University, Xi'an, Shaanxi 710062, China.ORCID http://orcid.org/0000-0003-1426-4042
Yuebing ZhengMaterials Science and Engineering Program and Texas Materials Institute, The University of Texas at Austin, Austin, TX 78712, USA. zheng@austin.utexas.edu.ORCID http://orcid.org/0000-0002-9168-9477

Funding

On-Chip Multiplexed Adhesion Frequency Assay for Measuring Receptor-Ligand Interactions on CellsDP2GM128446 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ZHENG, YUEBING · 2017 to 2017
$2.2M
NIGMS NIH HHS DP2 GM128446
6 · The paper itself

Abstract

Optical tweezers offer revolutionary opportunities for both fundamental and applied research in materials science, biology, and medical engineering. However, the requirement of a strongly focused and high-intensity laser beam results in potential photon-induced and thermal damages to target objects, including nanoparticles, cells, and biomolecules. Here, we report a new type of light-based tweezers, termed opto-refrigerative tweezers, which exploit solid-state optical refrigeration and thermophoresis to trap particles and molecules at the laser-generated cold region. While laser refrigeration can avoid photothermal heating, the use of a weakly focused laser beam can further reduce the photodamages to the target object. This novel and noninvasive optical tweezing technique will bring new possibilities in the optical control of nanomaterials and biomolecules for essential applications in nanotechnology, photonics, and life science.

Identifiers

PMID34172454
PMCPMC8232904

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.