Evidence map›Paper›PMID 34172441›Full record

ArticleScience advances2021

Engineered yeast tolerance enables efficient production from toxified lignocellulosic feedstocks.

Felix H Lam, Burcu Turanlı-Yıldız, Dany Liu, Michael G Resch, Gerald R Fink, Gregory Stephanopoulos

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Perspectives for Using COBioengineering (Basel, Switzerland) · 2023
    Review
  8. Article
  9. A Toolkit for Precise, Multigene Control inACS synthetic biology · 2022
    Article
  10. Review
  11. Review
  12. l-Lactic Acid Production Using EngineeredJournal of fungi (Basel, Switzerland) · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felix H LamDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID http://orcid.org/0000-0001-6585-3360
Burcu Turanlı-YıldızDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID http://orcid.org/0000-0002-3020-9177
Dany LiuDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID http://orcid.org/0000-0002-0859-6879
Michael G ReschNational Bioenergy Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
Gerald R FinkWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. gregstep@mit.edu gfink@wi.mit.edu.ORCID http://orcid.org/0000-0003-3704-2899
Gregory StephanopoulosDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. gregstep@mit.edu gfink@wi.mit.edu.ORCID http://orcid.org/0000-0001-6909-4568

Funding

REGULATION OF HISTIDINE BIOSYNTHESIS IN YEASTR01GM035010 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI FINK, GERALD R · 1985 to 2016
$9.9M
NIGMS NIH HHS R01 GM035010
6 · The paper itself

Abstract

Lignocellulosic biomass remains unharnessed for the production of renewable fuels and chemicals due to challenges in deconstruction and the toxicity its hydrolysates pose to fermentation microorganisms. Here, we show in

Identifiers

PMID34172441
PMCPMC8232913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.