Evidence map›Paper›PMID 34172141›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2021

Childhood Socioeconomic Status and Menarche: A Prospective Study.

Robert A Hiatt, Susan L Stewart, Julianna Deardorff, Elizabeth Danial, Ekland Abdiwahab, Susan M Pinney, Susan L Teitelbaum, Gayle C Windham, Mary S Wolff, Lawrence H Kushi and 1 more

Abstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Socioeconomic Status and Age at Menarche in Türkiye.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Neighborhood Racial and Economic Privilege and Timing of Pubertal Onset in Girls.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023
    Article
  10. The Impact of Macronutrient Intake on Sex Steroids During Onset of Puberty.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Robert A HiattDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California. Electronic address: Robert.Hiatt@ucsf.edu.
Susan L StewartDivision of Biostatistics, University of California Davis, Davis, California.
Julianna DeardorffDivision of Community Health Sciences, University of California Berkeley, School of Public Health, Berkeley, California.
Elizabeth DanialDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.
Ekland AbdiwahabDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.
Susan M PinneyDepartment of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Susan L TeitelbaumDepartment of Community and Preventive Medicine, Mt Sinai School of Medicine, New York, New York.
Gayle C WindhamDivision of Environmental and Occupational Health, California Department of Public Health, Richmond, California.
Mary S WolffDepartment of Community and Preventive Medicine, Mt Sinai School of Medicine, New York, New York.
Lawrence H KushiDivision of Research, Kaiser Permanente, Oakland, California.
Frank M BiroDivision of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI YADAV, JAGJIT S · 1992 to 2022
$35.4M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2014 to 2026
$21.3M
MOUNT SINAI INSTITUTES FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR029887 · NCRR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2009 to 2011
$19.2M
Bay Area Breast Cancer &the Environment Research CenterU01ES012801 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HIATT, ROBERT A · 2003 to 2010
$12.4M
Center for Environment and Mammary Gland DevelopmentU01ES012771 · NIEHS · FOX CHASE CANCER CENTER · PI RUSSO, JOSE · 2003 to 2009
$11.1M
Puberty &Cancer Initiation: Environment Diet &ObesityU01ES012770 · NIEHS · UNIVERSITY OF CINCINNATI · PI BORNSCHEIN, ROBERT L · 2003 to 2009
$9.0M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
PRENATAL PCB EXPOSURE &NEURODEVELOPMENTAL OUTCOMES IN ADOLESCENCE &ADULTHOODP01ES009584 · NIEHS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI WOLFF, MARY S · 1999 to 2009
$7.3M
Environmental and Genetic Determinants of PubertyU01ES019454 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WOLFF, MARY S · 2010 to 2016
$5.8M
Breast Cancer and the Environment Research CenterU01ES012800 · NIEHS · MICHIGAN STATE UNIVERSITY · PI HASLAM, SANDRA Z · 2003 to 2009
$5.6M
Environmental Epigenetics on PubertyU01ES019453 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI BIRO, FRANK M · 2010 to 2015
$5.4M
The CYGNET Study: Enviromental and Genetic Determinants of Maturation of GirlsU01ES019435 · NIEHS · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2010 to 2015
$4.9M
NCRR NIH HHS UL1 RR029887NICHD NIH HHS T32 HD049311NIEHS NIH HHS P01 ES009584NIEHS NIH HHS P30 ES006096NIEHS NIH HHS P30 ES023515NIEHS NIH HHS U01 ES012770NIEHS NIH HHS U01 ES012771NIEHS NIH HHS U01 ES012800NIEHS NIH HHS U01 ES012801NIEHS NIH HHS U01 ES019435NIEHS NIH HHS U01 ES019453NIEHS NIH HHS U01 ES019454NIEHS NIH HHS U01 ES019457
6 · The paper itself

Abstract

purposeThe relationship between socioeconomic status (SES) and menarche has implications for understanding social level influences on early life development and adult disease, including breast cancer, but remains ill defined. We report here results from the Breast Cancer and the Environment Research Program, which permitted a longitudinal study of age at menarche in relationship to childhood SES in a diverse cohort of 1,069 girls across three urban areas of the United States.

methodsWe assessed the association of SES index quintiles with age at pubertal onset with breast budding and subsequent tempo to the age at menarche between 2004 and 2015 using multiple-event Cox regression models to estimate hazard ratios and 95% confidence intervals.

resultsIn an unadjusted model, lower SES was predictive of both earlier pubertal onset and tempo and thus earlier age at menarche in trends across quintiles. After adjusting for the potentially mediating effects of body mass index, SES trends remained significant for both outcomes. After adjusting for both body mass index and race/ethnicity, the association with SES remained substantial for pubertal onset but was much diminished and nonsignificant for tempo and thus age at menarche.

conclusionsThese results suggest that a lower SES environment and social adversity affect the age at menarche primarily by hastening pubertal onset rather than by shortening tempo.

Indexed as

MenarchePubertyAdultBody Mass IndexChildFemaleHumansLongitudinal StudiesProspective StudiesSocial ClassUnited StatesBreast cancercohortobesitypubertyrace/ethnicitysocioeconomic status

Identifiers

PMID34172141
PMCPMC8243506

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.