Evidence map›Paper›PMID 34172050›Full record

ArticleParticle and fibre toxicology2021

Prolonged exposure to traffic-related particulate matter and gaseous pollutants implicate distinct molecular mechanisms of lung injury in rats.

Yu-Teng Jheng, Denise Utami Putri, Hsiao-Chi Chuang, Kang-Yun Lee, Hsiu-Chu Chou, San-Yuan Wang, Chia-Li Han

Open access · goldAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Article
  3. Chitosan Nanoparticle-EncapsulatedInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. The Effects and Pathogenesis of PM2.5 and Its Components on Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2023
    Review
  7. Deficiency of interleukin-6 receptor ameliorates PMEcotoxicology and environmental safety · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yu-Teng Jheng *Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Mailing address: 250 Wuxing St, Taipei, 11031, Taiwan.
Denise Utami Putri *International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hsiao-Chi ChuangSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Kang-Yun LeeDivision of Pulmonary Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hsiu-Chu ChouDepartment of Anatomy and Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
San-Yuan WangMaster Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Mailing address: 250 Wuxing St, Taipei, 11031, Taiwan.
Chia-Li HanMaster Program in Clinical Pharmacogenomics and Pharmacoproteomics, College of Pharmacy, Taipei Medical University, Mailing address: 250 Wuxing St, Taipei, 11031, Taiwan. was@tmu.edu.tw.ORCID 0000-0003-4644-5892
Taipei Medical University · TWTaipei Medical University-Shuang Ho Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposure to air pollution exerts direct effects on respiratory organs; however, molecular alterations underlying air pollution-induced pulmonary injury remain unclear. In this study, we investigated the effect of air pollution on the lung tissues of Sprague-Dawley rats with whole-body exposure to traffic-related PM

resultsRats in the 6-month PM

conclusionThis study explored several potential molecular features associated with early lung damage in response to traffic-related air pollution, which might be used to screen individuals more susceptible to air pollution.

Indexed as

Air PollutantsAir PollutionLung InjuryAnimalsEnvironmental ExposureEnvironmental PollutantsGasesParticulate MatterRatsRats, Sprague-DawleyAir PollutantsEnvironmental PollutantsGasesParticulate MatterGaseous pollutantLung injuryMolecular mechanismParticulate matterProteomicsTraffic-related air pollution

Identifiers

PMID34172050
PMCPMC8235648
OpenAlexW3176523205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.