Evidence map›Paper›PMID 34171990›Full record

ArticleBMC infectious diseases2021

Values and preferences for hepatitis C self-testing among people who inject drugs in Kyrgyzstan.

Guillermo Z Martínez-Pérez, Danil S Nikitin, Alla Bessonova, Emmanuel Fajardo, Sergei Bessonov, Sonjelle Shilton

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Guillermo Z Martínez-PérezDepartment of Physiatrics and Nursing, University of Zaragoza, Calle Domingo Miral s/n, 50009, Zaragoza, Spain.
Danil S NikitinGlobal Research Institute Foundation (GLORI), 125 Suyumbaev Street apt 21, 720011, Bishkek, Kyrgyzstan.
Alla BessonovaKyrgyz Network of Harm Reduction (KNHR), 21 Yug-2 Microdistrict apt 55, 720052, Bishkek, Kyrgyzstan.
Emmanuel FajardoFoundation for Innovative New Diagnostics, Chemin des Mines 9, 1202, Geneva, Switzerland.
Sergei BessonovKyrgyz Network of Harm Reduction (KNHR), 21 Yug-2 Microdistrict apt 55, 720052, Bishkek, Kyrgyzstan.
Sonjelle ShiltonFoundation for Innovative New Diagnostics, Chemin des Mines 9, 1202, Geneva, Switzerland. Sonjelle.Shilton@finddx.org.
Foundation for Innovative New Diagnostics · CHUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of hepatitis C virus (HCV) among people who inject drugs (PWID) continues to be a major public-health burden in this highly stigmatised population. To halt transmission of HCV, rapid HCV self-testing kits represent an innovative approach that could enable PWID to know their HCV status and seek treatment. As no HCV test has yet been licenced for self-administration, it is crucial to obtain knowledge around the factors that may deter or foster delivery of HCV self-testing among PWID in resource-constrained countries.

methodsA qualitative study to assess values and preferences relating to HCV self-testing was conducted in mid-2020 among PWID in the Bishkek and Chui regions of Kyrgyzstan. Forty-seven PWID participated in 15 individual interviews, two group interviews (n = 12) and one participatory action-research session (n = 20). Responses were analysed using a thematic analysis approach with 4 predefined themes: awareness of HCV and current HCV testing experiences, and acceptability and service delivery preferences for HCV self-testing. Informants' insights were analysed using a thematic analysis approach. This research received local ethics approval.

resultsAwareness of HCV is low and currently PWID prefer community-based HCV testing due to stigma encountered in other healthcare settings. HCV self-testing would be accepted and appreciated by PWID. Acceptability may increase if HCV self-testing: was delivered in pharmacies or by harm reduction associations; was free of charge; was oral rather than blood-based; included instructions with images and clear information on the test's accuracy; and was distributed alongside pre- and post-testing counselling with linkage to confirmatory testing support.

conclusionsHCV self-testing could increase awareness of and more frequent testing for HCV infection among PWID in Kyrgyzstan. It is recommended that peer-driven associations are involved in the delivery of any HCV self-testing. Furthermore, efforts should be maximised to end discrimination against PWID at the healthcare institutions responsible for confirmatory HCV testing and treatment provision.

Indexed as

Diagnostic Self EvaluationPatient PreferenceSubstance Abuse, IntravenousAdolescentAdultAgedAged, 80 and overFemaleHarm ReductionHepacivirusHepatitis CHumansKyrgyzstanMaleMiddle AgedPatient Acceptance of Health CareDiagnosticsFormative researchHepatitis CHepatitis C self-testingValues and preferences

Identifiers

PMID34171990
PMCPMC8233180
OpenAlexW3175928950

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.