Evidence map›Paper›PMID 34171922›Full record

ArticleInteractive cardiovascular and thoracic surgery2021

Comparing outcomes in patients with end-stage chronic obstructive pulmonary disease: single versus bilateral lung transplants.

Sudeep Mutyala, M Abul Kashem, Jay Kanaparthi, Gengo Sunagawa, Manish Suryapalam, Eros Leotta, Kenji Minakata, Stacey Brann, Norihisa Shigemura, Yoshiya Toyoda

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sudeep MutyalaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
M Abul KashemLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.ORCID 0000-0002-2342-029X
Jay KanaparthiLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Gengo SunagawaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.ORCID 0000-0003-4852-0702
Manish SuryapalamDivision of Cardiovascular Surgery and Transplant Surgery, Department of Surgery, Temple University Hospital, Philadelphia, PA, USA.
Eros LeottaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Kenji MinakataLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Stacey BrannLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.ORCID 0000-0003-3309-0797
Norihisa ShigemuraLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Yoshiya ToyodaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Temple University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDebate continues on whether a bilateral (BLT) or a single lung transplantation (SLT) is preferred for patients with end-stage chronic obstructive pulmonary disease (COPD). The purpose of this study is to examine the interplay between patient age and transplant type on survival outcomes.

methodsWe performed a retrospective study of lung transplants for COPD at our centre from February 2012 to March 2020 (n = 186). Demographics and clinical parameters were compared between patients based on their age (≤65 vs >65 years old) and type of transplant (single vs bilateral). Cox proportional hazards regression was also performed. P-values <0.05 were considered significant.

resultsOf the 186 patients with COPD who received lung transplants, 71 (38.2%) received BLTs and 115 (61.8%) received SLTs. There was no significant difference in survival outcomes when looking at patients with single versus BLTs (P = 0.870). There was also no difference in survival between the 2 age groups ≤65 versus > 65 years (P = 0.723). The Cox model itself also did not show a statistically significant improvement in survival outcomes (P = 0.126).

conclusionsLung transplant outcomes in patients with end-stage COPD demonstrated non-inferior results in patients with an SLT compared to patients with a BLT. When we compared the age groups, neither transplant type showed superior survival benefits, suggesting there may be some utility in an SLT in younger recipients.

Indexed as

Lung TransplantationPulmonary Disease, Chronic ObstructiveAgedHumansRetrospective StudiesBilateral lung transplantationChronic obstructive pulmonary diseaseSingle lung transplantationSurvival outcome

Identifiers

PMID34171922
PMCPMC8923376
OpenAlexW3173172396

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.