ArticleJournal of biomechanics2021
A MATLAB toolbox for muscle diffusion-tensor MRI tractography.
Article in Journal of biomechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Standardizing quantitative muscle MRI: an inter-vendor evaluation in healthy adults.Magma (New York, N.Y.) · 2026Article
- Diffusion tractography outside the brain: the road less travelled.Brain structure & function · 2026Review
- MRI-based 3D estimation of skeletal muscle architecture and strain during contraction.Journal of biomechanics · 2026Article
- A Comparison of Skeletal Muscle Diffusion Tensor Imaging Tractography Seeding Methods.NMR in biomedicine · 2025Article
- Improved DTI-Based Skeletal Muscle Architecture Estimation via Diffusion Weighted Image Denoising and First Eigenvector Map Smoothing.NMR in biomedicine · 2025Article
- A registration strategy to characterize DTI-observed changes in skeletal muscle architecture due to passive shortening.PloS one · 2025Article
- The impact of diffusion tensor imaging tractography settings on muscle fascicle architecture and diffusion parameter estimates: Tract length, completion, and curvature are most sensitive to tractography settings.NMR in biomedicine · 2024Article
- Magnetic Resonance Imaging Biomarkers of Muscle.Tomography (Ann Arbor, Mich.) · 2024Review
- A registration strategy to characterize DTI-observed changes in skeletal muscle architecture due to passive shortening.bioRxiv : the preprint server for biology · 2024Article
- Predicted effects of image acquisition and analysis conditions on DTMRI tractography-based muscle architecture estimates.Magnetic resonance in medicine · 2024Article
- Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging.Annals of biomedical engineering · 2024Article
- Sensitivity analyses of probabilistic and deterministic DTI tractography methodologies for studying arm muscle architecture.Magnetic resonance in medicine · 2024Article
- Quantitative Muscle Fascicle Tractography Using Brightness-Mode Ultrasound.Journal of applied biomechanics · 2023Article
- Time-dependent diffusion tensor imaging and diffusion modeling of age-related differences in the medial gastrocnemius and feasibility study of correlations to histopathology.NMR in biomedicine · 2023Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Diffusion-tensor MRI fiber tractography has been used to reconstruct skeletal muscle architecture, but remains a specialized technique using custom-written data processing routines. In this work, we describe the public release of a software toolbox having the following design objectives: accomplish the pre-processing tasks of file input, image registration, denoising, and diffusion-tensor calculation; allow muscle-specific methods for defining seed points; make fiber-tract architectural measurements referenced to tendinous structures; visualize fiber tracts and other muscle structures of interest; analyze the goodness of outcomes; and provide a programming structure that allows the addition of new capabilities in future versions. The proper function of the code was verified using simulated datasets. The toolbox capabilities for characterizing human muscle structure in vivo were demonstrated in a case study. These capabilities included measurements of muscle morphology; contractile and non-contractile tissue volumes; fiber-tract length, pennation angle, curvature; and the physiological cross-sectional area,. The free public release of this software is a first step in creating of a community of users who use these tools in studies of muscle physiology and biomechanics. Users may further contribute to code development. Along with simulated and actual datasets for benchmarking, these tools will further create mechanisms for enhancing scientific rigor and developing and validating new code features. Planned future developments include additional options for image pre-processing, development of a graphical user interface, analysis of architectural patterns during muscle contraction, and integration of functional imaging data.
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Registered trials
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