ArticleCell2021
Representational geometry of perceptual decisions in the monkey parietal cortex.
Article in Cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed, 114 citations in OpenAlex.
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- The inherent capacity of neurons to learn order relations and support abstract reasoning.Nature communications · 2026Article
- Stable readout of visual representations mediates flexible generalization.Nature communications · 2026Article
- Computational neural dynamics of goal-directed visual attention in macaques.Science advances · 2026Article
- The cost of efficiency in flexible neural representations.bioRxiv : the preprint server for biology · 2026Article
- Control of cortical population activity with patterned microstimulation.bioRxiv : the preprint server for biology · 2026Article
- Understanding the Brain as a Mentalizing Machine with a Symbol Grounding Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Hierarchical binding of cognition to action in the human basal ganglia-thalamic circuit.bioRxiv : the preprint server for biology · 2026Article
- The geometry of context-dependent biased decisions during learning.bioRxiv : the preprint server for biology · 2026Article
- From sensory to perceptual manifolds: The twist of neural geometry.Science advances · 2025Article
- Neural mechanisms of flexible perceptual inference.PLoS computational biology · 2025Article
- Three types of remapping with linear decoders: A population-geometric perspective.PLoS computational biology · 2025Article
- Multidimensional Representation Dynamics for Abstract Visual Objects in Encoded Tangram Paradigms.Brain sciences · 2025Article
- Three types of remapping with linear decoders: a population-geometric perspective.bioRxiv : the preprint server for biology · 2025Article
- A neural manifold view of the brain.Nature neuroscience · 2025Review
- Cognitive processes are disentangled at cortex-wide scales.bioRxiv : the preprint server for biology · 2025Article
- Unraveling the neural code: analysis of large-scale two-photon microscopy data.Microscopy (Oxford, England) · 2025Review
- Thinking as Analogy-Making: Toward a Neural Process Account of General Intelligence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Lateral intraparietal (LIP) neurons represent formation of perceptual decisions involving eye movements. In circuit models for these decisions, neural ensembles that encode actions compete to form decisions. Consequently, representation and readout of the decision variables (DVs) are implemented similarly for decisions with identical competing actions, irrespective of input and task context differences. Further, DVs are encoded as partially potentiated action plans through balance of activity of action-selective ensembles. Here, we test those core principles. We show that in a novel face-discrimination task, LIP firing rates decrease with supporting evidence, contrary to conventional motion-discrimination tasks. These opposite response patterns arise from similar mechanisms in which decisions form along curved population-response manifolds misaligned with action representations. These manifolds rotate in state space based on context, indicating distinct optimal readouts for different tasks. We show similar manifolds in lateral and medial prefrontal cortices, suggesting similar representational geometry across decision-making circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.