Evidence map›Paper›PMID 34171198›Full record

ReviewAnnual review of vision science2021

Imaging the Retinal Vasculature.

Stephen A Burns, Ann E Elsner, Thomas J Gast

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of vision science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Dissecting endothelial cell heterogeneity with new tools.Cell regeneration (London, England) · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Neurophotonics · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephen A BurnsIndiana University School of Optometry, Bloomington, Indiana 47405, USA; email: staburns@indiana.edu, aeelsner@indiana.edu, bugbane2@gmail.com.
Ann E ElsnerIndiana University School of Optometry, Bloomington, Indiana 47405, USA; email: staburns@indiana.edu, aeelsner@indiana.edu, bugbane2@gmail.com.
Thomas J GastIndiana University School of Optometry, Bloomington, Indiana 47405, USA; email: staburns@indiana.edu, aeelsner@indiana.edu, bugbane2@gmail.com.
Indiana University Bloomington · US

Funding

Adaptive Optics Imaging of Human Retinal Vascular Structure and FunctionR01EY024315 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2015 to 2024
$4.3M
NEI NIH HHS R01 EY024315
6 · The paper itself

Abstract

Advances in retinal imaging are enabling researchers and clinicians to make precise noninvasive measurements of the retinal vasculature in vivo. This includes measurements of capillary blood flow, the regulation of blood flow, and the delivery of oxygen, as well as mapping of perfused blood vessels. These advances promise to revolutionize our understanding of vascular regulation, as well as the management of retinal vascular diseases. This review provides an overview of imaging and optical measurements of the function and structure of the ocular vasculature. We include general characteristics of vascular systems with an emphasis on the eye and its unique status. The functions of vascular systems are discussed, along with physical principles governing flow and its regulation. Vascular measurement techniques based on reflectance and absorption are briefly introduced, emphasizing ways of generating contrast. One of the prime ways to enhance contrast within vessels is to use techniques sensitive to the motion of cells, allowing precise measurements of perfusion and blood velocity. Finally, we provide a brief introduction to retinal vascular diseases.

Indexed as

Retinal DiseasesTomography, Optical CoherenceCapillariesHumansRetinaRetinal Vesselsadaptive opticsblood flowophthalmoscopyoptical coherence tomographyretinastructure and functionvasculature

Identifiers

PMID34171198
PMCPMC8446336
OpenAlexW3177459389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.