Evidence map›Paper›PMID 34171191›Full record

ArticleJournal of agricultural and food chemistry2021

Protein Biomarkers of Bovine Defective Meats at a Glance: Gel-Free Hybrid Quadrupole-Orbitrap Analysis for Rapid Screening.

Enrique Sentandreu, Claudia Fuente-García, Olga Pardo, Mamen Oliván, Núria León, Noelia Aldai, Vicent Yusà, Miguel A Sentandreu

Open access · hybridAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Enrique SentandreuInstituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC). Calle Agustín Escardino 7, 46980 Paterna, Valencia, Spain.
Claudia Fuente-GarcíaInstituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC). Calle Agustín Escardino 7, 46980 Paterna, Valencia, Spain.
Olga PardoFoundation for the Promotion of Health and Biomedical Research of the Valencia Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain.
Mamen OlivánServicio Regional de Investigación y Desarrollo Alimentario (SERIDA), Carretera de Oviedo, s/n, 33300 Villaviciosa, Asturias, Spain.
Núria LeónPublic Health Laboratory of Valencia, Av. Catalunya, 21, 46020 Valencia, Spain.
Noelia AldaiLactiker Research Group, Department of Pharmacy and Food Sciences, University of the Basque Country (UPV/EHU), Paseo de la Universidad 7, Vitoria-Gasteiz 01006, Spain.
Vicent YusàFoundation for the Promotion of Health and Biomedical Research of the Valencia Region, FISABIO-Public Health, Av. Catalunya, 21, 46020 Valencia, Spain.
Miguel A SentandreuInstituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC). Calle Agustín Escardino 7, 46980 Paterna, Valencia, Spain.ORCID https://orcid.org/0000-0001-5792-0148
Instituto de Agroquímica y Tecnología de Alimentos · ESUniversitat de València · ESUniversity of the Basque Country · ESServicio Regional de Investigación y Desarrollo Agroalimentario · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An understanding of biological mechanisms that could be involved in the stress response of animal cattle prior to slaughter is critical to create effective strategies aiming at the production of high-quality meat. The sarcoplasmic proteome of directly extracted samples from normal and high ultimate pH (pHu) meat groups was studied through a straightforward gel-free strategy supported by liquid chromatography hybrid quadrupole-Orbitrap high-resolution mass spectrometry (LC-HRMS) analysis. A stepped proteomic pipeline combining rapid biomarker hunting supported by qualitative protein Mascot scores followed by targeted label-free peptide quantification revealed 26 descriptors that characterized meat groups assayed. The functional study of the proposed biomarkers suggested their relevant role in metabolic, chaperone/stress-related, muscle contractility/fiber organization, and transport activities. The efficiency, flexibility, rapidity, and easiness of the methodology proposed can positively contribute to the creation of innovative proteomic alternatives addressing meat quality assessment.

Indexed as

Muscle ProteinsProteomicsAnimalsBiomarkersCattleMeatMuscle, SkeletalBiomarkersMuscle Proteinshigh-resolution proteomicsmeat biomarkersmeat quality assessmentpre-slaughter stressrapid proteomic screening

Identifiers

PMID34171191
PMCPMC8278482
OpenAlexW3175723684

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.